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methyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1353049-81-6 Structure
  • Basic information

    1. Product Name: methyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
    2. Synonyms: methyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
    3. CAS NO:1353049-81-6
    4. Molecular Formula:
    5. Molecular Weight: 612.741
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1353049-81-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 655.8±55.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.18±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: methyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate(CAS DataBase Reference)
    10. NIST Chemistry Reference: methyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate(1353049-81-6)
    11. EPA Substance Registry System: methyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate(1353049-81-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1353049-81-6(Hazardous Substances Data)

1353049-81-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1353049-81-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,3,0,4 and 9 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1353049-81:
(9*1)+(8*3)+(7*5)+(6*3)+(5*0)+(4*4)+(3*9)+(2*8)+(1*1)=146
146 % 10 = 6
So 1353049-81-6 is a valid CAS Registry Number.

1353049-81-6Relevant articles and documents

Synthesis and evaluation of atorvastatin esters as prodrugs metabolically activated by human carboxylesterases

Mizoi, Kenta,Takahashi, Masato,Haba, Masami,Hosokawa, Masakiyo

supporting information, p. 921 - 923 (2016/05/24)

We synthesized 11 kinds of prodrug with an esterified carboxylic acid moiety of atorvastatin in moderate to high yields. We discovered that they underwent metabolic activation specifically by the human carboxylesterase 1 (CES1) isozyme. The results sugges

Asymmetric synthesis of the HMG-CoA reductase inhibitor atorvastatin calcium: An organocatalytic anhydride desymmetrization and cyanide-free side chain elongation approach

Chen, Xiaofei,Xiong, Fangjun,Chen, Wenxue,He, Qiuqin,Chen, Fener

, p. 2723 - 2728 (2014/04/17)

An efficient asymmetric synthesis of atorvastatin calcium has been achieved from commercially available diethyl 3-hydroxyglutarate through a novel approach that involves an organocatalytic enantioselective cyclic anhydride desymmetrization to establish C(

STATIN DERIVATIVES

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Page/Page column 27-28, (2012/01/13)

Dinitrate statins having improved pharmacological activity are described. They can be employed for treating and/or preventing several diseases, in particular acute coronary syndromes, neurodegenerative disorders as well as for reducing cholesterol levels.

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