cas 13551-73-0, 5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE | Articles data ｜lookchem

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13551-73-0

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TRPML MODULATORS
The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.
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Paragraph 0335

(2021/06/26)

(5,6-DIHYDRO)PYRIMIDO[4,5-E]INDOLIZINES
The invention relates to a compound of Formula (I) wherein, R1 and R2 independently are selected from the group consisting of optionally substituted (6-10C)aryl and (1-5C)heteroaryl groups. The compounds can be used in pharmaceutical compositions, in particular in the treatment of cancer.
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Page/Page column 40

(2015/11/17)

Synthesis and properties of 5-chloro-4-nitropyrazoles
The nitration of 5-chloropyrazoles with a mixture of 100% nitric acid and 65% oleum or a mixture of 60% nitric acid and polyphosphoric acid gave substituted 5-chloro-4-nitropyrazoles in 45-91% yield. The nitration of 3-aryl-5-halopyrazoles was accompanied
Bozhenkov,Savosik,Larina,Mirskova,Levkovskaya
p. 901 - 906
(2007/10/03)

CHARACTERISTIC FEATURES OF DIAZOTATION OF 5,4- AND 4,5-AMINONITROPYRAZOLES AND REDUCTION OF 5-ARYLAZO-1-METHYL-4-NITROPYRAZOLES
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Perevalov, V. P.,Baryshnenkova, L. I.,Denisova, E. A.,Andreeva, M. A.,Stepanov, B. I.
p. 1397
(2007/10/02)

5-Substituted derivatives of dipyrazolo[1,5-a:4',3'-e]pyrazine-6-carboxylic acids and esters
New 5-substituted derivatives of dipyrazolo[1,5-a:4',3'-e]pyrazine-6-carboxylic acid, esters and their salts have the formula STR1 R1 is hydrogen, lower alkyl or phenyl-lower alkylene; R2 and R3 each is hydrogen or lower alkyl; X is oxygen or sulfur; and R4 is hydrogen, lower alkyl, phenyl-lower alkylene or amino-lower alkylene. The new compounds are useful as anti-inflammatory agents and immunosuppressive agents.
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(2008/06/13)

4-Nitropyrazoles
Covers a method of inducing abscission of fruit by applying a chemical composition containing an effective amount of a 4-nitropyrazole as the active ingredient in an agronomically acceptable carrier. Also covers certain 4-nitropyrazoles.
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(2008/06/13)

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Chemical Properties

Melting Point: 75 °C
Boiling Point: 275.7 °C at 760 mmHg
Flash Point:120.6 °C
Density: 1.55g/cm³
Storage Temp.:2-8°C
Vapor Pressure: 0.00841mmHg at 25°C
Refractive Index: 1.625
BRN: 149733
PSA: 63.64000
LogP: 1.81330

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