135590-91-9

Basic information

• Product Name: Mefenpyr-diethyl
• Synonyms: 1-(2,4-Dichlorophenyl)-4,5-dihydro-5-methyl-1H-pyrazole-3,5-dicarboxylic acid diethyl ester;MEFENPYR-DIETHYL;EMBARK;1H-Pyrazole-3,5-dicarboxylic acid, 1-(2,4-dichlorophenyl)-4,5-dihydro-5-methyl-, diethyl ester;mefenpyr-diethyl (bsi, pa iso);Herbicide Safener Mefenpyr-Diethyl;HOE-107892;Mefenpyr-diethyl [iso]
• CAS NO: 135590-91-9
• Molecular Formula: C₁₆H₁₈Cl₂N₂O₄
• Molecular Weight: 373.23
• EINECS: 201-006-8
• Mol File: 135590-91-9.mol

Chemical Properties

• Melting Point: 50-52°
• Boiling Point: 451.089 °C at 760 mmHg
• Flash Point: 226.611 °C
• Appearance: /
• Density: 1.345 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: 0-6°C
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: -5.89±0.70(Predicted)
• CAS DataBase Reference: Mefenpyr-diethyl(CAS DataBase Reference)
• NIST Chemistry Reference: Mefenpyr-diethyl(135590-91-9)
• EPA Substance Registry System: Mefenpyr-diethyl(135590-91-9)

Safety Data

• Hazard Codes: N
• Statements: 51/53
• Safety Statements: 60-61
• RIDADR: UN 3077
• WGK Germany: 3
• RTECS: UQ6473000
• HazardClass: 9
• PackingGroup: III
• Hazardous Substances Data: 135590-91-9(Hazardous Substances Data)

Usage

Uses

Used in Agriculture:
Mefenpyr-diethyl is used as a herbicide safener for modern agriculture to provide a resistant breaking solution. It is employed in herbicidal and herbicide-safener combinations, allowing for the selective control of weeds while minimizing damage to the desired crop. This application helps improve crop yield and quality, making it a valuable tool in contemporary farming practices.

InChI:InChI=1/C16H18Cl2N2O4/c1-4-23-14(21)12-9-16(3,15(22)24-5-2)20(19-12)13-7-6-10(17)8-11(13)18/h6-8H,4-5,9H2,1-3H3

Upstream product

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Relevant articles and documents

Preparation method of mefenpyr-diethyl

The invention relates to a preparation method of mefenpyr-diethyl, which specifically comprises the following steps: (a) mixing ethyl 2-chloroacetoacetate, 2,4-dichloroaniline, inorganic acid and water, and then adding a sodium nitrite aqueous solution to form a reaction system, and performing diazotization and substitution reactions, so as to obtain ethyl 2-chloro-2-(2,4-dichlorobenzene diazo) acetoacetate; and (b) adding an inorganic base into the reaction system to adjust the pH value to 5-7, then adding a bicarbonate aqueous solution to carry out a hydrolysis reaction to obtain ethyl 2-chloro-2-(2,4-dichlorobenzylidenehydrazino)acetate, then sequentially adding a polymerization inhibitor, ethyl methacrylate and the bicarbonate aqueous solution to carry out cyclization, and carrying outpost-treatment to obtain the mefenpyr-diethyl. Compared with the prior art, the intermediate generated through diazotization and substitution is stable, the intermediate does not need to be separated, the method is easy and convenient to operate, reaction conditions are mild, sodium bicarbonate (or potassium bicarbonate) is used for hydrolysis, the raw material price is low, and the dosage is small.

Synthesis method of mefenpyr-diethyl

The invention relates to a synthesis method of mefenpyr-diethyl. The method comprises the steps of carrying out a reaction among 2,4-dichlorophenylhydrazine hydrochloride, ethyl glyoxalate and alkaliin a solvent, and carrying out a [3+2] cycloaddition rea

NOVEL FORM OF MEFENPYR-DIETHYL,PROCESS FOR PREPARATION AND USE THEREOF

A crystalline form of mefenpyr-diethyl of formula (I), the crystal preparation process, the analyses of the crystal through various analytical methods and using the crystal to prepare stable agrochemical formulation are provided. The use of various solvents towards the crystalline form preparation conditions is also provided.

Process for the preparation of 1-phenylpyrazoline-3-carboxylic acid derivatives

There is described a process for the preparation of 1-phenylpyrazoline-3-carboxylic acid derivatives of the formula III by means of base-catalyzed reaction of hydrazones of the formula I with olefins of the formula II STR1 where Ph, R1, R2, R3, X and Y have the following meanings: Ph is optionally substituted phenyl, R1 is hydrogen or alkyl, R2 and R3 independently of one another are hydrogen, halogen, cyano, an optionally substituted organic radical, or R2 and R3 together with the carbon atom to which they are attached form a saturated or partially saturated ring having 5 or 6 atoms, x is amino, hydroxyl, alkoxy, cycloalkoxy, alkylamino, dialkylamino, alkyloxyalkyloxy, trialkylsilyloxy or trialkylsilylmethyloxy and Y is chlorine or bromine. The reaction is carried out in a two-phase system composed of an organic and an aqueous phase using a sterically hindered amine and, if appropriate, a further base. These 1-phenylpyrazoline-3-carboxylic acid derivatives are employed as so-called safeners, i.e. agents which protect the useful plants in agricultural and silvicultural crops from undesired damage associated with the effect of herbicides.

Pyrazolines for protecting crop plants against herbicides

Compounds of the formula (I) STR1 where X, n, R1, R2 and R3 are as defined in claim 1 are suitable as antidotes against phytotoxic secondary effects of herbicides in crop plants without adversely affecting the action of the herbicides against harmful plants.