13575-73-0 Usage
Uses
Used in Pharmaceutical Synthesis:
Trans-2-Amino-2,3-dihydro-1H-inden-1-ol hydrochloride is used as a reagent in the synthesis of pharmaceuticals for its ability to contribute to the formation of complex drug molecules, enhancing the development of new medications.
Used in Organic Synthesis:
As a building block in organic synthesis, trans-2-Amino-2,3-dihydro-1H-inden-1-ol hydrochloride is employed to construct various organic compounds, facilitating the creation of a wide range of chemical products.
Used in Research and Development:
In the research and development of new pharmaceutical products, trans-2-Amino-2,3-dihydro-1H-inden-1-ol hydrochloride is utilized for its potential to advance scientific understanding and innovation in drug discovery, playing a key role in the design and synthesis of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 13575-73-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,7 and 5 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13575-73:
(7*1)+(6*3)+(5*5)+(4*7)+(3*5)+(2*7)+(1*3)=110
110 % 10 = 0
So 13575-73-0 is a valid CAS Registry Number.
13575-73-0Relevant articles and documents
Efficient diastereoselective synthesis of cis-2-amino-1-indanol derivatives and cis- and trans-1-amino-2-indanol via Pd-catalyzed hydrogenation
Nguyen, Thi Ha,Ma, Eunsook
supporting information, p. 3717 - 3728 (2021/11/01)
(±)-cis-2-amino-1-indanol was diastereoselectively synthesized from 1,2-indanedion-2-oxime in ethanol at 25 °C under 10% Pd/C-catalyzed hydrogenation conditions. Under the same hydrogenation condition, 1,2-indanedion-2-oxime and their derivatives having one and/or two electron-donating groups in aliphatic or aromatic part of indanyl ring were diastereoselectively reduced to racemic cis-2-amino-1-indanol derivatives. From 1,2-indanedion-1-oxime, (±)-trans-1-amino-2-indanol was obtained in ethanol at 25 °C over a 10% Pd/BaSO4 catalyst. In contrast, the 10% Pd/BaSO4-catalyzed hydrogenation reaction in ethanol at 45 °C afforded cis-1-hydroxyamino-2-indanol from 1,2-indanedion-1-oxime, followed by reduction to form (±)-cis-1-amino-2-indanol. The diastereoselectivity of β-aminoindanols was dependent on the Pd catalyst, reaction temperature, and pH of the reaction medium.
