135938-65-7Relevant articles and documents
NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES
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Paragraph 0414, (2020/01/08)
The present invention discloses compounds according to Formula I: wherein R1, R2a, X, Y, and Z are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising th
INDOLE DERIVATIVES
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, (2008/06/13)
Disclosed are compounds of formula I STR1 wherein R 1 is a hydrogen atom, a C 1-C 6 alkyl group, benzyl or an indolyl carbonyl group, R 2 is a saturated or unsaturated 5-or 8-membered heterocyclic group containing as a hetero atom one or more nitrogen atoms, the heterocyclic group is optionally substituted at an N or C atom by a C 1-C 6 alkyl or aralkyl group, n is an integer of 1 to 5 and one or more hydrogen atoms, in an alkylene chain--(CH 2) n--are optionally substituted by a C. sub.1-C 6 alkyl, phenyl and/or hydroxyl group, physiologically acceptable salts and quaternary ammonium salts thereof. The compounds are selective antagonists of 5-HT 3 receptors and are useful in the treatment of psychotic disorders, neurotic diseases, gastric stasis symptoms, gastrointestinal disorders, nausea and vomiting.