Welcome to LookChem.com Sign In|Join Free

CAS

  • or

136015-39-9

(S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone, a chiral oxazolidinone derivative with the chemical formula C11H13NO3, is a compound that features a benzyl moiety and a hydroxymethyl group. It has been explored for its potential as a chiral auxiliary in asymmetric synthesis and as a building block in the creation of various pharmaceutical compounds. Its unique structure and properties render it a valuable intermediate in organic synthesis, particularly for the synthesis of chiral compounds. Furthermore, the oxazolidinone ring system has been investigated for its potential as a pharmacophore in drug discovery and development.

136015-39-9 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 136015-39-9 Structure

  • Basic information

    1. Product Name: (S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone
    2. Synonyms: (S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone
    3. CAS NO:136015-39-9
    4. Molecular Formula: C11H13NO3
    5. Molecular Weight: 207.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 136015-39-9.mol

  • Chemical Properties

    1. Melting Point: 66 °C(Solv: pentane (109-66-0))
    2. Boiling Point: 456.6±28.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.262±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 14.49±0.10(Predicted)
    10. CAS DataBase Reference: (S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone(CAS DataBase Reference)
    11. NIST Chemistry Reference: (S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone(136015-39-9)
    12. EPA Substance Registry System: (S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone(136015-39-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 136015-39-9(Hazardous Substances Data)

136015-39-9 Usage

Uses

Used in Pharmaceutical Industry:
(S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone is used as a chiral auxiliary for enhancing the selectivity and yield in asymmetric synthesis, which is crucial for producing enantiomerically pure compounds that are often required for pharmaceutical applications.
Used in Organic Synthesis:
(S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone is used as a building block in the preparation of various pharmaceutical compounds, contributing to the development of new drugs with improved efficacy and selectivity.
Used in Drug Discovery and Development:
(S)-3-Benzyl-4-(hydroxymethyl)-2-oxazolidinone is used as a potential pharmacophore in drug discovery and development, due to its oxazolidinone ring system, which may play a role in the interaction with biological targets and contribute to the compound's therapeutic effects.

Check Digit Verification of cas no

The CAS Registry Mumber 136015-39-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,0,1 and 5 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 136015-39:
(8*1)+(7*3)+(6*6)+(5*0)+(4*1)+(3*5)+(2*3)+(1*9)=99
99 % 10 = 9
So 136015-39-9 is a valid CAS Registry Number.

136015-39-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (4S)-3-benzyl-4-hydroxymethyl-oxazolidin-2-one

1.2 Other means of identification

Product number -
Other names (4S)-3-benzyl-4-hydroxymethyl-2-oxazolidinone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:136015-39-9 SDS

136015-39-9Relevant articles and documents

Heterolignans: Stereoselective synthesis of an 11-amino analog of azaelliptitoxin

Routier, Julie,Calancea, Mihaela,David, Marion,Vallee, Yannick,Denis, Jean-Noel

supporting information; experimental part, p. 5687 - 5691 (2009/05/31)

The 11-amino-azaelliptitoxin analog (11R,11aS,5R)-15 has been prepared stereoselectively in eight steps and 24% over-all yield from commercially available (S)-glycidol (7) via the original enantiopure chiral α-amino aldehyde 9, used as chiral precursor fo

Nucleophilic ring opening of cyclic sulphamidites

Gautun,Carlsen

, p. 1667 - 1674 (2007/10/02)

The cyclic sulphamidities (2S,4S)- and (2R,4S)-3-benzyl-4-benzyloxymethyl-2-oxo-1,2,3-oxathiazolidine 1 were prepared from S-glycidol in 60-66% overall yield. Nucleophilic ring opening of 1 by cyanide, azide and benzyloxy anions have been studied with respect to regio and stereospecificity. A mild procedure for benzylation of alcohols was introduced.

Synthesis of Optically Pure 4-Hydroxymethyloxazolidinone as Chiral Serinol Synthon from Glycidol

Katsumura, Shigeo,Kondo, Akihiro,Han, Quingjun

, p. 1245 - 1248 (2007/10/02)

Optically pure 3-benzyl-4-hydroxymethyl-2-oxazolidinone and 4-benzoyloxymethyl-2-oxazolidinone as chiral serinol synthons were synthesized from optically active glycidol by intramolecular cyclization via 2,3-epoxycarbamates with strict SN2 beha

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 136015-39-9