170956-47-5Relevant academic research and scientific papers
Nucleophilic ring opening of cyclic sulphamidites
Gautun,Carlsen
, p. 1667 - 1674 (1995)
The cyclic sulphamidities (2S,4S)- and (2R,4S)-3-benzyl-4-benzyloxymethyl-2-oxo-1,2,3-oxathiazolidine 1 were prepared from S-glycidol in 60-66% overall yield. Nucleophilic ring opening of 1 by cyanide, azide and benzyloxy anions have been studied with respect to regio and stereospecificity. A mild procedure for benzylation of alcohols was introduced.
