The biginelli reaction with an imidazolium-tagged recyclable iron catalyst: Kinetics, mechanism, and antitumoral activity
The present work describes the synthesis, characterization, and application of a new ion-tagged iron catalyst. The catalyst was employed in the Biginelli reaction with impressive performance. High yields have been achieved when the reaction was carried ou
Ramos, Luciana M.,Guido, Bruna C.,Nobrega, Catharine C.,Corrêa, José R.,Silva, Rafael G.,De Oliveira, Heibbe C. B.,Gomes, Alexandre F.,Gozzo, Fábio C.,Neto, Brenno A. D.
supporting information
p. 4156 - 4168
(2013/05/08)
QSAR analysis of 2-oxo-1,2,3,4-tetrahydropyrimidine analogues of antibacterials
QSAR analysis of two sets of analogues of 2-oxo-1,2,3,4- tetrahydropyrimidine was performed to investigate the relationship between their physicochemical parameters and antibacterial activity. Predictive and statistically significant models were generated
Sawant, Ramesh L.,Bhatia, Manish S.
experimental part
p. 1361 - 1373
(2010/04/28)
UREAS IN ORGANIC SYNTHESIS. II. SYNTHESIS OF HYDROGENATED ACRIDINE-1,8-DIONES AND 1,4-DIHYDROPYRIDINES BY REACTION OF UREAS WITH 1,3-DICARBONYL COMPOUNDS.
Urea and its methyl derivatives are convenient reagents in a new single-stage method for the synthesis of compounds of the 1,4-dihydropyridine and pyridine series.Like benzaldehyde, under the discovered conditions benzyl alcohol gives hydrogenated 9-phenyltetramethylacridine-1,8-dione in reaction with urea and dimedone.
Bakibaev, A. A.,Filimonov, V. D.
p. 736 - 740
(2007/10/02)
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