- Synthesis of (+)-2,8-dihydroxyethyl-1,4,7,10-tetraoxaspiro[5.5]undecane from (R)-4-hydroxymethyl-2,2-dimethyl-1,3-dioxane
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Selective transformations of diethyl (R)-malate afforded (R)-4-hydroxymethyl 2,2-dimethyl-1,3-dioxane 7 in reasonable yield. Subsequent synthesis of (2S,6R,8S)-2,8-di hydroxyethyl-1,4,7,10-tetraoxaspiro[5.5]undecane 11 was achieved using precursor 7.
- Sauret-Cladiere, Sandrine,Jeminet, Georges
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