Tetrahedron Asymmetry p. 417 - 423 (1997)
Update date:2022-08-03
Topics:
Sauret-Cladiere, Sandrine
Jeminet, Georges
Selective transformations of diethyl (R)-malate afforded (R)-4-hydroxymethyl 2,2-dimethyl-1,3-dioxane 7 in reasonable yield. Subsequent synthesis of (2S,6R,8S)-2,8-di hydroxyethyl-1,4,7,10-tetraoxaspiro[5.5]undecane 11 was achieved using precursor 7.
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