1,4-dihydropyridine derivatives, a process for their preparation and their use for influencing the blood flow
The invention relates to new 1,4-dihydropyridine derivatives of the general formula I STR1 in which R1, R2, R3 and n have the meaning stated in the patent claims. The compounds of the invention have a vasodilatory effect and are therefore suitable for the treatment of hypertension. Some of the compounds have a vasoconstrictory effect and can therefore be used for the treatment of hypotension.
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(2008/06/13)
Synthesis of 3-1,4-Dihydropyridine-3,5-dicarboxylate Derivaties as Calcium Channel Modulators
1,4-Dihydropyridine (DHP) derivatives with a 1,2-benzisothiazol-3-one 1,1-dioxide group, linked through an alkylene bridge to the C-3 carboxylate of the DHP ring, with both vasoconstricting and vasorelaxant properties were obtained.In blocking Ca2+/
Sunkel, Carlos E.,Casa-Juana, Miguel Fau de,Santos, Luis,Garcia, Antonio G.,Artalejo, Cristina R.,et al.
p. 2407 - 2414
(2007/10/02)
New 1,4-dihydropyridine derivatives, a process for their preparation and their use for influencing the blood flow
The invention relates to new 1,4-dihydropyridine derivatives of the general formula I in which R1, R2, R3 and n have the meaning stated in the patent claims. The compounds of the invention have a vasodilatory effect and are therefore suitable for the treatment of hypertension. Some of the compounds have a vasoconstrictory effect and can therefore be used for the treatment of hypotension.
-
(2008/06/13)
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