Palladium-catalyzed paraformaldehyde insertion: A three-component synthesis of benzofurans
An efficient procedure for 2-aroylbenzofuran preparation from 2-bromophenols, phenacyl bromides and paraformaldehyde is described. The cheap and stable paraformaldehyde served as the carbon source via an in situ formylation reaction.
Cheng, Xiufang,Peng, Yi,Wu, Jun,Deng, Guo-Jun
supporting information
p. 2819 - 2823
(2016/03/12)
5-phenyl-1-benzofuran-2-yl derivatives: Synthesis, antimicrobial, and antioxidant activity
Previously unknown biphenyl containing 5-phenyl-1-benzofuran-2-yl derivatives; methanones (2a-i), tertiary alcohols (3a-l), and carbinols (4a-f) were synthesized and evaluated for their antimicrobial and antioxidant activities to study the effect of funct