- Chemoselective synthesis of highly substituted 1,2-allenyl ketones, furans, and 2-alkynyl ketones from reaction of lithium selenolates with 1-(1-alkynyl)cyclopropyl ketones and electrophiles
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A homo-Michael addition reaction of lithium selenolates with 1-(1-alkynyl)cyclopropyl ketones and the subsequent reaction with electrophiles such as PhSeBr, NFSI and NCS is reported. Based on the nature of electrophiles, this reaction may afford highly substituted 1,2-allenyl ketones or furans (E+ = PhSe+) and 2-alkynyl ketones (E+ = F +, Cl+, active halides) as the final products, respectively.
- Xu, Jianfeng,Zhu, Shugao,Wu, Luling,Huang, Xian
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scheme or table
p. 3705 - 3714
(2012/05/31)
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