1379028-84-8

Basic information

• Product Name: 2,6-Difluoro-4-Methyl aniline
• Synonyms: 2,6-Difluoro-4-Methyl aniline;2,6-Difluoro-4-methylbenzenamine
• CAS NO: 1379028-84-8
• Molecular Formula: C₇H₇F₂N
• Molecular Weight: 143.1339864
• Mol File: 1379028-84-8.mol

Chemical Properties

• Boiling Point: 172.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.229±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 2.24±0.10(Predicted)
• CAS DataBase Reference: 2,6-Difluoro-4-Methyl aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Difluoro-4-Methyl aniline(1379028-84-8)
• EPA Substance Registry System: 2,6-Difluoro-4-Methyl aniline(1379028-84-8)

Safety Data

• Hazardous Substances Data: 1379028-84-8(Hazardous Substances Data)

Usage

Uses

Used in Chemical Production:
2,6-Difluoro-4-Methyl aniline is used as a key intermediate in the synthesis of various industrial chemicals. Its unique structure and properties make it a valuable component in the production of dyes, pharmaceuticals, and agricultural products, contributing to the development of a wide range of applications across different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 2,6-Difluoro-4-Methyl aniline is utilized as a building block for the development of new drugs. Its specific chemical properties allow for the creation of novel compounds with potential therapeutic effects, enhancing the discovery and innovation of medications for various medical conditions.
Used in Dye Industry:
2,6-Difluoro-4-Methyl aniline is employed as a precursor in the manufacturing of dyes. Its fluorinated and methylated structure imparts unique color characteristics and stability to the resulting dyes, making them suitable for use in various applications such as textiles, plastics, and printing inks.
Used in Agricultural Products:
In the agricultural sector, 2,6-Difluoro-4-Methyl aniline is used in the formulation of agrochemicals, including pesticides and herbicides. Its chemical properties enable the development of effective and targeted products that can protect crops and enhance agricultural productivity while minimizing environmental impact.
Overall, 2,6-Difluoro-4-Methyl aniline plays a significant role in various industries, showcasing its versatility and importance in the synthesis of a broad spectrum of products. Its applications in chemical production, pharmaceuticals, dyes, and agricultural products highlight its potential to contribute to technological advancements and improvements in different fields.

Upstream product

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Relevant articles and documents

Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties

Red-shifted azobenzene scaffolds have emerged as useful molecular photoswitches to expand potential applications of photopharmacological tool compounds. As one of them, tetra-ortho-fluoro azobenzene is well compatible for the design of visible-light-responsive systems, providing stable and bidirectional photoconversions and tissue-compatible characteristics. Using the unsubstituted azobenzene core and its tetra-ortho-fluorinated analogue, we have developed a set of uni- and bivalent photoswitchable toolbox derivatives of the highly potent muscarinic acetylcholine receptor agonist iperoxo. We investigated the impact of the substitution pattern on receptor activity and evaluated the different binding modes. Compounds 9b and 15b show excellent photochemical properties and biological activity as fluorination of the azobenzene core alters not only the photochromic behavior but also the pharmacological profile at the muscarinic M1 receptor. These findings demonstrate that incorporation of fluorinated azobenzenes not just may alter photophysical properties but can exhibit a considerably different biological profile that has to be carefully investigated.