- INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL
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The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis
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- COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE
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The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and solid forms of the compounds of this invention. The compounds of this invention have formula I-A or I-B: wherein the variables are as defined herein.
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- FULLERENE FILM AND FULLERENE POLYMER BOTH PRODUCED FROM FULLERENE DERIVATIVE AND PROCESSES FOR PRODUCING THESE
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Disclosed is a fullerene film which can be easily formed by a wet process without deteriorating the intrinsic properties of a fullerene by using a fullerene derivative as a raw material. Also disclosed are a fullerene polymer, a method for producing a ful
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Page/Page column 15
(2010/12/29)
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- MODULATORS OF HCV REPLICATION
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The present invention is directed to the use of compounds of formula (I): 1 R X 3 R Y ( I) 2 R 5 where X, Y, R1, R2 and R3 are defined therein, which can act as modulators of viral replication and/or virus production, especially of the hepatitis C virus (HCV), in a cell based system.
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Page/Page column 17; 29
(2008/06/13)
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- Xanthamide fluorescent dyes
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Two derivatives of fluorescein, termed "xanthamides," were prepared from fluorescein, an inexpensive dye. Relative to fluorescein, which contains a 6-phenolic OH and a 2′-carboxyl, the first derivative (5) contains a carboxymethyl ether at the 6-position
- Gao, Jianxin,Wang, Poguang,Giese, Roger W.
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p. 6397 - 6401
(2007/10/03)
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