HYDROXY- AND AMINOMETHYLATION OF 1-METHYL-2-AMINO-4-IMIDAZOLINONE
The corresponding imidazolo-1,3,5-triazines are formed as a result of the aminomethylation of 1-methyl-2-amino-4-imidazolinone (creatinine) and its 5-benzylidene derivative with paraformaldehyde and primary aliphatic amines.Hydroxymethylation is directed to the C(5) position of the creatinine heteroring.
Ramsh, S. M.,Zheltonog, N. G.,Khrabrova, E. S.,Golovanova, E. A.
p. 601 - 603
(2007/10/02)
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