138716-46-8Relevant articles and documents
Identification and optimisation of 5-amino-7-aryldihydro-1,4-diazepines as 5-HT2A ligands
Swain, Christopher J.,Teran, Ana,Maroto, Marta,Cabello, Angeles
, p. 6058 - 6062 (2007/10/03)
A several series of low molecular weight 5-HT2A leads were identified from an analysis of HTS data, the exploration of SAR and optimization of one series using parallel synthesis are described, affording compound 22 (5-HT2A IC50 1.1 nM).