138890-87-6

Basic information

• Product Name: 3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-2-thiophenesulfonamide
• Synonyms: 3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-2-thiophenesulfonamide;3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)thiophene-2-sulfonamide
• CAS NO: 138890-87-6
• Molecular Formula: C11H17NO4S2
• Molecular Weight: 291.38698
• Mol File: 138890-87-6.mol

Chemical Properties

• Appearance: /
• Density: 1.278
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-2-thiophenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-2-thiophenesulfonamide(138890-87-6)
• EPA Substance Registry System: 3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-2-thiophenesulfonamide(138890-87-6)

Safety Data

• Hazardous Substances Data: 138890-87-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-2-thiophenesulfonamide is utilized as a building block in the synthesis of potential drug candidates. Its structural components, including the thiophene ring and dioxane group, may confer specific biological activities that are valuable in the development of new medications.
Used in Organic Synthesis:
In the realm of organic synthesis, 3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-2-thiophenesulfonamide may serve as a key intermediate for the creation of more complex organic molecules. Its unique functional groups can be manipulated to form a variety of compounds with different properties and applications.
Used in Medicinal Chemistry:
3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-2-thiophenesulfonamide also finds applications in medicinal chemistry, where it can be employed to explore the structure-activity relationships of various biologically active molecules. Its incorporation into different chemical frameworks can lead to the discovery of novel therapeutic agents with improved efficacy and selectivity.
The precise uses and properties of 3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)-2-thiophenesulfonamide are contingent upon the specific context and application in which it is employed, highlighting its versatility in multiple scientific disciplines.

Upstream product

• 138890-86-5 3-(2,5,5-Trimethyl-l,3-dioxane-2-yl)thiophene 

Downstream Products

• 138890-88-7 3-Acetylthiophene-2-sulfonamide 

Relevant articles and documents

Process for the preparation of (R)-(+)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide.

Disclosed herein is an improved process for the preparation of (R)-(+)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide (Brinzolamide) and novel intermediates thereof.

SULFONAMIDE INHIBITORS OF CARBONIC ANHYDRASE

The present invention relates to new sulfonamide inhibitors of carbonic anhydrase activity, pharmaceutical compositions thereof, and methods of use thereof.

IMPROVED PROCESS FOR THE PREPARATION OF (R)-(+)-4-(ETHYIAMINO)-3,4-DIHYDRO-2-(3- METHOXYPROPYL)-2H-THIENO[3,2-E]-L,2-THIAZINE-6-SULFONAMIDE-L,L-DIOXIDE

Disclosed herein is an improved process for the preparation of (R)-(+)-4- (Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e]-1,2-thiazine-6- sulfonamide- 1,1 -dioxide (Brinzolamide) and novel intermediates thereof.

Carbonic anhydrase inhibitors

Compounds of the following formula are disclosed: Compounds of Formula I are the topic of this invention: STR1 Wherein G, J and the two atoms of the thiophene ring to which they are attached form a six-membered ring chosen from STR2 The compounds are usef

Sulfonamides useful as carbonic anhydrase inhibitors

Sulfonamides and pharmaceutical compositions containing the compounds useful in controlling intraocular pressure are disclosed. Methods for controlling intraocular pressure through administration of the compositions are also disclosed.

Sulfonamides useful as carbonic anhydrase inhibitors

Sulfonamides and pharmaceutical compositions containing the compounds useful in controlling intraocular pressure are disclosed. Methods for controlling intraocular pressure through administration of the compositions are also disclosed.

Thiophene sulfonamides useful as carbonic anhydrase inhibitors

Thiophene sulfonamides and pharmaceutical compositions containing the compounds useful in controlling intraocular pressure are disclosed. Methods for controlling intraocular pressure through administration of the compositions are also disclosed.