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13898-58-3

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Discovery of meta-amido bromophenols as new antitubercular agents
A series of meta-amido bromophenol derivatives were designed and synthesized. The compounds were found to potently inhibit the growth of Mycobacterium tuberculosis H37Ra. They also exhibited moderate inhibitory activity against Mycobacterium tuberculosis H37Rv and multidrug-resistant strains. The compounds did not show inhibitory activity against normal Gram-positive and Gram-negative bacteria. Moderate cytotoxicities and good metabolic stability were observed for the selected compounds. The results demonstrated meta-amido bromophenols as a new class of antitubercular agents with good potentials.
Liang, Jie,Tang, Yun-xiang,Tang, Xiang-zheng,Liang, Hua-ju,Gao, Yamin,Fang, Cuiting,Zhang, Tian-yu,Yan, Ming
p. 372 - 381
(2019/05/07)

Thermoplastic polymer composition
The invention provides a compound conforming to the structure of Formula (C) The invention also provides a thermoplastic polymer composition comprising a polyolefin polymer and a compound conforming to the structure of Formula (C) as a nucleating agent.
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Page/Page column 60

(2015/12/17)

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Chemical Properties

Melting Point: 260-261°
Boiling Point: 375.8°Cat760mmHg
Flash Point:181.1°C
Density: 1.434g/cm³
Vapor Pressure: 2.58E-06mmHg at 25°C
Refractive Index: 1.5780 (estimate)
PKA: 3.14±0.10(Predicted)
PSA: 86.63000
LogP: 2.41570

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