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1-Acetyl-4-(methylamino)piperidine, also known as acetylmethadol, is a synthetic opioid analgesic drug closely related to methadone. It is characterized by its chemical structure that enables it to act as a μ-opioid receptor agonist, producing analgesic effects by binding to opioid receptors in the brain and spinal cord. 1-Acetyl-4-(methylamino)piperidine has a shorter duration of action and is less likely to accumulate in the body compared to methadone, making it a distinct entity in the realm of opioid medications.

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  • 139062-96-7 Structure
  • Basic information

    1. Product Name: 1-Acetyl-4-(methylamino)piperidine
    2. Synonyms: 1-ACETYL-N-METHYLPIPERIDIN-4-AMINE;4-N-METHYLAMINO-1-ACETYL-PIPERIDINE;4-Piperidinamine, 1-acetyl-N-methyl- (9CI);4-N-Methylamino-1-Acetyl;1-ACETYL-4-(METHYLAMINO)PIPERIDINE;1-Aceyl-N-methyl-piperidine-4-amine;1-[4-(Methylamino)piperidin-1-yl]ethan-1-one, 1-Acetyl-N-methylpiperidin-4-amine;1-(4-(MethylaMino)piperidin-1-yl)ethanone hydrochloride
    3. CAS NO:139062-96-7
    4. Molecular Formula: C8H16N2O
    5. Molecular Weight: 156.23
    6. EINECS: N/A
    7. Product Categories: ACETYLGROUP
    8. Mol File: 139062-96-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 280.2 °C at 760 mmHg
    3. Flash Point: 123.3 °C
    4. Appearance: /
    5. Density: 1.01g/cm3
    6. Vapor Pressure: 0.00383mmHg at 25°C
    7. Refractive Index: 1.49
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 9.70±0.20(Predicted)
    11. CAS DataBase Reference: 1-Acetyl-4-(methylamino)piperidine(CAS DataBase Reference)
    12. NIST Chemistry Reference: 1-Acetyl-4-(methylamino)piperidine(139062-96-7)
    13. EPA Substance Registry System: 1-Acetyl-4-(methylamino)piperidine(139062-96-7)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. RIDADR: UN3259
    5. WGK Germany:
    6. RTECS:
    7. HazardClass: 8
    8. PackingGroup: III
    9. Hazardous Substances Data: 139062-96-7(Hazardous Substances Data)

139062-96-7 Usage

Uses

Used in Pain Management:
1-Acetyl-4-(methylamino)piperidine is used as an analgesic agent for the treatment of severe chronic pain. Its mechanism of action involves binding to μ-opioid receptors, which helps in reducing the perception of pain and providing relief to patients suffering from intense and persistent pain conditions.
Used in Opioid Addiction Management:
In the field of addiction medicine, 1-Acetyl-4-(methylamino)piperidine serves as a crucial component in managing opioid addiction. It is used as a maintenance therapy to help individuals dependent on opioids to gradually reduce their dependence and withdrawal symptoms, facilitating a smoother transition towards recovery. Despite its potential for abuse and dependence, it is an FDA-approved medication for this purpose, highlighting its importance in the clinical management of opioid use disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 139062-96-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,0,6 and 2 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 139062-96:
(8*1)+(7*3)+(6*9)+(5*0)+(4*6)+(3*2)+(2*9)+(1*6)=137
137 % 10 = 7
So 139062-96-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H16N2O/c1-7(11)10-5-3-8(9-2)4-6-10/h8-9H,3-6H2,1-2H3

139062-96-7 Well-known Company Product Price

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  • Alfa Aesar

  • (H50985)  1-Acetyl-4-(methylamino)piperidine   

  • 139062-96-7

  • 250mg

  • 821.0CNY

  • Detail
  • Alfa Aesar

  • (H50985)  1-Acetyl-4-(methylamino)piperidine   

  • 139062-96-7

  • 1g

  • 2963.0CNY

  • Detail

139062-96-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[4-(methylamino)piperidin-1-yl]ethanone

1.2 Other means of identification

Product number -
Other names 1-ACETYL-4-(METHYLAMINO)PIPERIDINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:139062-96-7 SDS

139062-96-7Upstream product

139062-96-7Relevant articles and documents

Aminopiperidine indanyl and benzocyclobutene compounds

-

, (2008/06/13)

The invention relates to new compounds of formula I: STR1 in which: m represents zero, 1, 2, 3 or 4, n and p represent zero, 1 or 2, W represents an oxygen atom, an --NH-- radical, or a single bond, R represents a benzocyclobuten-1-yl radical, or an indanyl radical, a 2,3-dihydrobenzofuran-2-yl R1 represents a hydrogen atom, an alkyl radical having from 1 to 6 carbon atoms, or an aryl radical, and R2 represents a hydrogen atom, an alkyl radical, an alkenyl radical, a cycloalkyl radical, a benzyl radical, a phenyl radical, an aralkyl radical, an alkoxyalkyl radical or a polyhalogenated alkyl radical, the optical isomers thereof and the addition salts thereof with a pharmaceutically acceptable organic or mineral acid, and medicaments containing the same.

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