70724-74-2

Usage

Uses

Used in Pharmaceutical Industry:
MethanesulfonaMide, N-Methyl-N-4-piperidinylis used as a pharmaceutical intermediate for the synthesis of various drugs. It plays a key role in the production of medicines for the treatment of different medical conditions, contributing to the development of new therapeutic options for patients.

Upstream product

• 139062-96-7 1-Acetyl-4-methylaminopiperidine 
• 124-63-0 methanesulfonyl chloride 
• 147539-41-1 4-methylamino-piperidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

PURINE DERIVATIVES USEFUL AS PI3 KINASE INHIBITORS

This invention provides a compound which is a purine of formula (Ia) or (Ib): and the pharmaceutically acceptable salts thereof that are inhibitors of PI3K and a selective for the p110δ isoform, which is a class Ia PI3 kinase, over other class Ia PI3 kinases and over class Ib kinases. The compounds may be used to treat diseases and disorders arisi from abnormal cell growth, function or behaviour associated with PI3 kinase such as cance immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.

CHIRAL CIS-IMIDAZOLINES

There are provided compounds of Formula (I), or the pharmaceutically acceptable salts thereof, wherein X, Y, Z, V1, V2, R1, R2, R3, R4 and R5 are as herein described, processes for obtaining said compounds and pharmaceutical preparations containing them. These compounds are useful as anticancer agents, in particular as agents in the treatment of solid tumors.

1-PIPERIDINOPHTHALAZINES AS CARDIAC STIMULANTS

A series of 1-piperidinophthalazine derivatives as phosphodiesterase inhibitors and cardiac stimulants