139157-71-4 Usage
Chemical class
Hexahydropyrimidine derivatives
Contains
Nitroimidazole group
Associated properties
Anti-parasitic, anti-cancer, and anti-inflammatory
Activity
Promising against multidrug-resistant cancer cells
Potential use
Chemotherapy agent
Anti-inflammatory effects
Demonstrated in preclinical studies
Check Digit Verification of cas no
The CAS Registry Mumber 139157-71-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,1,5 and 7 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 139157-71:
(8*1)+(7*3)+(6*9)+(5*1)+(4*5)+(3*7)+(2*7)+(1*1)=144
144 % 10 = 4
So 139157-71-4 is a valid CAS Registry Number.
139157-71-4Relevant articles and documents
Preparation and antiparasitic activity of new imidazoles bearing dioxane or hexahydropyrimidine moiety
Vanelle,Maldonado,Crozet,Senouki,Delmas,Gasquet,Timon-David
, p. 709 - 714 (2007/10/02)
5-Nitro-1,3-dioxane and 5-nitrohexahydropyrimidine salts are found to be suitable nucleophiles for S(RN)1 reactions. From C-alkylation products, base-promoted nitrous acid elimination and acid-catalyzed cleavage of the resulting acetals afford new compounds. Only the imidazole derivatives exhibit significant amoebicide and trichomonacide activities. Structure-activity relationships are discussed.
