Acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions: evidence for organoaluminum intermediates
The Friedel-Crafts acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions has been reinvestigated. Evidence is presented in support of the hypothesis that when AlCl3 is used as the Lewis acid, acylation proceeds via reaction of
Huffman, John W.,Smith, Valerie J.,Padgett, Lea W.
p. 2104 - 2112
(2008/09/18)
A facile, highly efficient synthesis of fully N-confused calix[5]pyrrole
Fully N-confused calix[5]pyrroles 3 are prepared in high yield by the oligomerization of 3-hydroxyphenylmethylpyrrole 2 under acid-catalysed conditions at room temperature.
3-ACYL-1-TOSYLPYRROLES AS EXCELLENT PRECURSORS OF 3-VINYLIDENEPYRROLES
Two simple general methods for the synthesis of 3-vinylidenepyrroles 4a - c both starting from 3-acyl-1-tosylpyrroles have been developed.The simplest term of this class, 3-(1-methylethenyl)pyrrole, 4a, and the congeners 3-(1-phenylethenyl)pyrrole, 4b, an