139261-90-8

Basic information

• Product Name: PHENYL-[1-(TOLUENE-4-SULFONYL)-1H-PYRROL-3-YL]-METHANONE
• Synonyms: 3-BENZOYL-1-TOSYLPYRROLE;PHENYL-[1-(TOLUENE-4-SULFONYL)-1H-PYRROL-3-YL]-METHANONE;3-Benzoyl-1-[(4-methylphenyl)sulphonyl]pyrrole;3-Benzoyl-1-[(4-methylphenyl)sulphonyl]pyrrole 96%;Phenyl(1-tosyl-1H-pyrrol-3-yl)Methanone;3-Benzoyl-1-[(4-methylphenyl)sulphonyl]pyrrole96%;3-Benzoyl-1-[(4-methylphenyl)sulfonyl]pyrrole;3-benzoyl-1-(4-methylbenzenesulfonyl)-1H-pyrrole
• CAS NO: 139261-90-8
• Molecular Formula: C₁₈H₁₅NO₃S
• Molecular Weight: 325.38
• Product Categories: Azoles;blocks
• Mol File: 139261-90-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 94-96
• Boiling Point: 517.9 °C at 760 mmHg
• Flash Point: 267 °C
• Appearance: /
• Density: 1.23 g/cm³
• Vapor Pressure: 7.88E-11mmHg at 25°C
• Refractive Index: 1.614
• Storage Temp.: Keep Cold
• CAS DataBase Reference: PHENYL-[1-(TOLUENE-4-SULFONYL)-1H-PYRROL-3-YL]-METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL-[1-(TOLUENE-4-SULFONYL)-1H-PYRROL-3-YL]-METHANONE(139261-90-8)
• EPA Substance Registry System: PHENYL-[1-(TOLUENE-4-SULFONYL)-1H-PYRROL-3-YL]-METHANONE(139261-90-8)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 139261-90-8(Hazardous Substances Data)

Usage

Uses

3-Benzoyl-1-tosylpyrrole is an intermediate in the synthesis of rac Ketorolac 6-Benzoyl Isomer (K235620). rac Ketorolac 6-Benzoyl Isomer (Ketorolac EP Impurity C) is an isomeric impurity of Ketorolac (K235620).

InChI:InChI=1/C18H15NO3S/c1-14-7-9-17(10-8-14)23(21,22)19-12-11-16(13-19)18(20)15-5-3-2-4-6-15/h2-13H,1H3

Upstream product

• 17639-64-4 N-p-toluenesulfonylpyrrole 
• 98-88-4 benzoyl chloride 

Downstream Products

• 158782-29-7 3-(1-phenylethenyl)-1-tosylpyrrole 
• 7126-41-2 3-benzoylpyrrole 
• 62128-30-7 (1-methyl-1H-pyrrol-3-yl)(phenyl)methanone 

Relevant articles and documents

Acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions: evidence for organoaluminum intermediates

The Friedel-Crafts acylation of N-p-toluenesulfonylpyrrole under Friedel-Crafts conditions has been reinvestigated. Evidence is presented in support of the hypothesis that when AlCl3 is used as the Lewis acid, acylation proceeds via reaction of

3-ACYL-1-TOSYLPYRROLES AS EXCELLENT PRECURSORS OF 3-VINYLIDENEPYRROLES

Two simple general methods for the synthesis of 3-vinylidenepyrroles 4a - c both starting from 3-acyl-1-tosylpyrroles have been developed.The simplest term of this class, 3-(1-methylethenyl)pyrrole, 4a, and the congeners 3-(1-phenylethenyl)pyrrole, 4b, an