139386-35-9Relevant articles and documents
BCL-2 INHIBITOR
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Paragraph 0985-0986, (2021/10/22)
Disclosed herein is a compound of Formula (I) for inhibiting both Bcl-2 wild type and mutated Bcl-2, in particular, Bcl-2 G101V and D103Y, and a method of using the compound disclosed herein for treating dysregulated apoptotic diseases.
Simple and efficient access to 3-ethoxycarbonylpyrroles, naphthofurans
Pancote, Camila G.,De Carvalho, Bruno S.,Luchez, Cibele V.,Fernandes, Joao P.S.,Politi, Mario J.,Brandt, Carlos A.
experimental part, p. 3963 - 3966 (2010/03/26)
An efficient method was developed for the synthesis of pyrrole and furan derivatives from enamines, phenols, and naphthols. The key steps involve iodocyclization and alumina-induced dehydroiodination reactions. Georg Thieme Verlag Stuttgart.
Synthetic studies on naturally occurring coumarins. II. Synthesis of 6,7-dimethoxy- and 7,8-dimethoxy-5-[(E)-3-oxo-1-butenyl]coumarins
Ishii,Ishikawa,Wada,Miyazaki,Kaneko,Harayama
, p. 2614 - 2619 (2007/10/02)
In connection with studies on the structure elucidation of the so-called Reisch's coumarin isolated from Toddalia asiatica, syntheses of two coumarins (4 and 5) were accomplished via the routes shown in Charts 2 and 3, respectively. Melting points and NMR data of the synthesized coumarins (4 and 5) and of related coumarins (5-methoxysuberenon, toddalenone, and Reisch's coumarin) are given in Table I, suggesting that so-called Reisch's coumarin might be 4.
