139439-03-5

Basic information

• Product Name: 2-Pyridinemethanamine,alpha-2-propenyl-(9CI)
• Synonyms: 2-Pyridinemethanamine,alpha-2-propenyl-(9CI);1-(pyridin-2-yl)but-3-en-1-amine
• CAS NO: 139439-03-5
• Molecular Formula: C9H12N2
• Molecular Weight: 148.20498
• Product Categories: PYRIDINE
• Mol File: 139439-03-5.mol

Chemical Properties

• Boiling Point: 229.4±28.0 °C(Predicted)
• Appearance: /
• Density: 1.001±0.06 g/cm3(Predicted)
• PKA: 8.77±0.39(Predicted)
• CAS DataBase Reference: 2-Pyridinemethanamine,alpha-2-propenyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinemethanamine,alpha-2-propenyl-(9CI)(139439-03-5)
• EPA Substance Registry System: 2-Pyridinemethanamine,alpha-2-propenyl-(9CI)(139439-03-5)

Safety Data

• Hazardous Substances Data: 139439-03-5(Hazardous Substances Data)

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 72824-04-5 2-Allyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 3731-51-9 2-(Aminomethyl)pyridine 
• 88328-13-6 1-phenyl-N-(2-(pyridin-2-yl)methyl)methanimine 

Relevant articles and documents

METHODS OF PREPARING PRIMARY, SECONDARY AND TERTIARY CARBINAMINE COMPOUNDS IN THE PRESENCE OF AMMONIA

The present application relates to novel methods for the preparation of primary, secondary and tertiary carbinamine compounds, particularly the preparation of compounds of formulae I, IV and VI, from a carbonyl compound of formula II in the presence of ammonia or an ammonium equivalent of the formula NH4+X-, by way of allylation, crotylation, arylation, reductive amination and catalytic hydrogenation.

METHODS OF PREPARING SECONDARY CARBINAMINE COMPOUNDS WITH BORONIC ACIDS

The present application relates to novel methods for the preparation of secondary carbinamine compounds, particularly the preparation of secondary carbinamine compounds of the formula Ia, formula Ib or formula IV from aldehydes of the formula II and boronic acids of the formula III or formula V, in the presence of ammonia or an ammonia equivalent of the formula NH4+X-.

α-aminoallylation of aldehydes in aqueous ammonia

α-Aminoallylation of aldehydes in aqueous ammonia has been developed; commercial aqueous ammonia was successfully used, and this method does not require anhydrous conditions thus leading to easy and practical operations.

α-aminoallylation of aldehydes with ammonia: Stereoselective synthesis of homoallylic primary amines

Three-component reactions of aldehydes, ammonia, and allylboronates were found to provide homoallylic primary amines in high yields with high chemo- and stereoselectivities. A two-step, one-pot, stereoselective synthesis of an uncommon α-amino acid, alloisoleucine, was achieved utilizing this reaction. Copyright

Solid-liquid phase transfer catalytic synthesis VII: The synthesis of α-substituted-2-pyridylmethylamine via the alkylation of benzaldehyde imine

The anion derived from the benzaldehyde imine 2 reacts with alkyl halide to form alkylated products 3; Hydrolysis of 3 gives α-alkyl-2 pyridylmethylamine in 34-53% overall yield.