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  • 1398662-62-8 Structure
  • Basic information

    1. Product Name: C14H15ClFN3O
    2. Synonyms: C14H15ClFN3O
    3. CAS NO:1398662-62-8
    4. Molecular Formula:
    5. Molecular Weight: 295.744
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1398662-62-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C14H15ClFN3O(CAS DataBase Reference)
    10. NIST Chemistry Reference: C14H15ClFN3O(1398662-62-8)
    11. EPA Substance Registry System: C14H15ClFN3O(1398662-62-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1398662-62-8(Hazardous Substances Data)

1398662-62-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1398662-62-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,8,6,6 and 2 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1398662-62:
(9*1)+(8*3)+(7*9)+(6*8)+(5*6)+(4*6)+(3*2)+(2*6)+(1*2)=218
218 % 10 = 8
So 1398662-62-8 is a valid CAS Registry Number.

1398662-62-8Downstream Products

1398662-62-8Relevant articles and documents

Novel 5-fluorouracil derivatives: Synthesis and cytotoxic activity of 2-butoxy-4-substituted 5-fluoropyrimidines

Sun, Jian,Zhang, Shi-Jie,Li, Hai-Bo,Zhou, Wei,Hu, Wei-Xiao,Shan, Shang

, p. 1349 - 1354 (2013/07/28)

Twenty two new 5-fluorouracil (5-FU) derivatives, 2-butoxy-4-substituted 5-fluoropyrimidines, were synthesized and characterized by IR, 1H NMR, MS, HRMS. All compounds were preliminarily evaluated by MTT assay on human liver BEL-7402 cancer cell line in vitro. Ten compounds were selected to test their cytotoxic activity against A549, HL-60 and MCF-7 cancer cell lines in vitro. These compounds were more sensitive to BEL-7402 than other cell lines, particularly, cytotoxic activity of compounds 6b, 6d-f, 6p, 6s-u were in sub-micromolar scale. The highest cytotoxic potency against A549, HL-60 and MCF-7 was shown by 2-butoxy-4-chloro-5- fluoropyrimidine (5) with IC 50 values of 0.10, 1.66 and 0.59 μM, respectively. Compounds 6d and 6e were effective against MCF-7 with IC50 9.73 μM and HL-60 with IC50 8.83 μM, respectively.

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