140645-53-0

Basic information

• Product Name: 2-AMINOMETHYL-4-BOC-MORPHOLINE
• Synonyms: TERT-BUTYL 2-(AMINOMETHYL)MORPHOLINE-4-CARBOXYLATE;TERTIO-BUTYL 2-(AMINOMETHYL)MORPHOLINE-4-CARBOXYLATE;2-AMINOMETHYL-4-BOC-MORPHOLINE;2-(AMINOMETHYL)MORPHOLINE, 4-BOC PROTECTED;BUTTPARK 90\06-25;4-BOC-2-AMINOMETHYLMORPHOLINE ;2-Aminomethyl-morpholine-4-carboxylic acid tert-butyl ester;N-Boc-2-aminomethylmorpholine
• CAS NO: 140645-53-0
• Molecular Formula: C₁₀H₂₀N₂O₃
• Molecular Weight: 216.28
• Product Categories: pharmacetical
• Mol File: 140645-53-0.mol

Chemical Properties

• Boiling Point: 310.723 °C at 760 mmHg
• Flash Point: 141.72 °C
• Appearance: /
• Density: 1.079 g/cm³
• Vapor Pressure: 0.000589mmHg at 25°C
• Refractive Index: 1.477
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.37±0.29(Predicted)
• CAS DataBase Reference: 2-AMINOMETHYL-4-BOC-MORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOMETHYL-4-BOC-MORPHOLINE(140645-53-0)
• EPA Substance Registry System: 2-AMINOMETHYL-4-BOC-MORPHOLINE(140645-53-0)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN2811
• Hazardous Substances Data: 140645-53-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-AMINOMETHYL-4-BOC-MORPHOLINE is used as a reagent for the synthesis of novel small molecules that activate satellite cell proliferation and enhance the repair of damaged muscle. This application is particularly relevant in the development of treatments for muscle-related disorders and injuries, as well as in the field of sports medicine and rehabilitation.

InChI:InChI=1/C10H20N2O3/c1-10(2,3)15-9(13)12-4-5-14-8(6-11)7-12/h8H,4-7,11H2,1-3H3

Upstream product

• 876147-52-3 N-[[4-(tert-butoxycarbonyl)morpholin-2-yl]methyl]phthalimide 

Downstream Products

• 1184662-14-3 4-amino-N-[{4-(tert-butoxycarbonyl)-2-morpholinyl}methyl]-5-chloro-2-methoxybenzamide 
• 1207540-17-7 (morpholin-2-yl-methyl)-[7-(4-morpholin-4-yl-phenyl)-[1,6]naphthyridin-5-yl]-amine 
• 876148-26-4 N-(morpholin-2-ylmethyl)-2-(4-chlorophenyl)-4-methylthiazole-5-carboxamide 
• 876148-25-3 N-[[4-(tert-butoxycarbonyl)morpholin-2-yl]methyl]-2-(4-chlorophenyl)-4-methylthiazole-5-carboxamide 
• 1416984-78-5 C₁₇H₂₂Cl₂N₂O₄ 
• 1137477-07-6 methyl 6-((5-cyanopyrazin-2-yl)amino)-4-((morpholin-2-ylmethyl)amino)nicotinate 

Relevant articles and documents

AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

Disclosed is a compound having a strong affinity to serotonin-4 receptors, which is useful as an enterokinesis-promoting agent or a digestive tract function-improving agent. Specifically, disclosed is a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof. Also specifically disclosed is a pharmaceutical composition containing a compound represented by Formula (1) or a pharmaceutically acceptable salt thereof. [In Formula (1), Ar represents a group represented by Formula (Ar-1) or Formula (Ar-2).]

NOVEL CYCLIC AMINOBENZOIC ACID DERIVATIVE

The present invention relates to cyclic amino benzoic acid derivatives which are effective in therapy of lipid metabolism abnormality, diabetes and the like as a human peroxisome proliferators-activated receptor (PPAR) agonist, in particular, as an agonist against human PPARα isoform, and addition salts thereof, and pharmaceutical compositions containing these compounds. A cyclic amino benzoic acid derivative represented by the general formula (1) [wherein a ring Ar represents an aryl group which may have substituent, or the like; Y represents a C1-C4 alkylene, C2-C4 alkenylene, C2-C4 alkynylene, or the like; Z represents an oxygen atom, sulfur atom or - (CH2)n- (n represents 0,1 or 2) ; X represents a hydrogen atom, halogen atom, lower alkyl group which may be substituted with a halogen atom, or the like; R represents a hydrogen atom or lower alkyl group, and -COOR substitutes for an ortho position or metha position of binding position of ring W] or a pharmaceutically acceptable salt thereof.

MUTILIN DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

The invention is intended to provide a novel compound which is useful as an antibacterial agent and a manufacturing intermediate thereof and relates to a mutilin derivative represented by the formula (I) which is useful as an antibacterial agent against a multidrug resistant organism, a manufacturing intermediate thereof and the like. In the formula (I), R1 represents an ethyl group or a vinyl group, P1 represent H or a protecting group for a hydroxy group, R2 and R3 represent H or the like, G represents CH2 or the like, A represents -S-, -SO2-, -O- or the like, m represents an integer of 0 to 4, the Q1 ring represents a saturated heterocyclic group, R4 represents H, a lower alkyl group or the like, and W represents a group represented by the formula (W-1) or an amino protection group. In the formula (W-1), X represents a lower alkylene chain, a single bond or the like, Z1 represents CH or the like, Z2, Z3 and Z4 represent N or the like, and Y1 and Y2 represent H, an amino group, a group represented by the formula (Y-1) or the like. In the formula (Y-1), the Q2 ring represents a saturated heterocyclic group, and R9 and R10 represents H, a lower alkyl group or the like. (I) (W-1) (Y-1)