140715-57-7 Usage
Uses
Used in Organic Synthesis:
2-(6-BROMOHEXYL)-5-NITROISOINDOLINE-1,3-DIONE is used as a building block in organic synthesis for the creation of various chemical compounds. Its structural features, including the bromine atom and the nitro group, allow for versatile chemical reactions and modifications, making it a valuable component in the synthesis of new molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(6-BROMOHEXYL)-5-NITROISOINDOLINE-1,3-DIONE is used as a potential candidate for the development of pharmaceuticals. Its structural features and biological activity suggest that it may have therapeutic applications, and further research is needed to explore its potential as a drug molecule.
Used in Drug Discovery and Development:
2-(6-BROMOHEXYL)-5-NITROISOINDOLINE-1,3-DIONE is used as a target for drug discovery and development due to its unique combination of functional groups. Researchers are interested in investigating its potential as a lead compound for the creation of new drugs, particularly in the areas of organic synthesis and medicinal chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(6-BROMOHEXYL)-5-NITROISOINDOLINE-1,3-DIONE is used as a starting material for the synthesis of new drug candidates. Its structural features and potential biological activity make it a promising compound for the development of innovative therapeutic agents.
Used in Research and Development:
2-(6-BROMOHEXYL)-5-NITROISOINDOLINE-1,3-DIONE is used as a research tool in the field of drug discovery and development. Scientists and researchers utilize this compound to study its properties, reactivity, and potential applications in the creation of new pharmaceuticals and other chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 140715-57-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,7,1 and 5 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 140715-57:
(8*1)+(7*4)+(6*0)+(5*7)+(4*1)+(3*5)+(2*5)+(1*7)=107
107 % 10 = 7
So 140715-57-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H15BrN2O4/c15-7-3-1-2-4-8-16-13(18)11-6-5-10(17(20)21)9-12(11)14(16)19/h5-6,9H,1-4,7-8H2
140715-57-7Relevant articles and documents
Central cholinergic agents. I. Potent acetylcholinesterase inhibitors, 2-[ω-[N-alkyl-N-(ω-phenylalkyl)amino]alkyl]-1H-isoindole-1,3(2H)-dion es, based on a new hypothesis of the enzyme's active site
Ishihara,Kato,Goto
, p. 3225 - 3235 (2007/10/02)
It has been suggested that the active site of acetylcholinesterase contains a hydrophobic binding site (HBS-1), which is closely adjacent to both the anionic and the esteratic sites. In this paper, we assumed that there exists another hydrophobic binding site (HBS-2), some distance removed from the anionic site. On this assumption, a new working hypothesis was proposed for the design of acetylcholinesterase inhibitors. A series of 2-[ω-[N-alkyl-N-(ω-phenylalkyl)amino]alkyl]-1H-isoindole-1,3(2H)-dion es was designed based on this hypothesis and tested for its inhibitory activities on acetylcholinesterase. Some in this series were revealed to be more potent than physostigmine. Optimum activity was found to be associated with a five carbon chain length separating the benzylamino group from the 1H-isoindole-1,3(2H)-dione (phthalimide) moiety. Quantitative study of substitution effect on the phthalimide moiety revealed that hydrophilic and electron-withdrawing groups enhance the activity.
