629-03-8Relevant articles and documents
Stable and easily available sulfide surrogates allow a stereoselective activation of alcohols
Brutiu, Bogdan R.,Drescher, Martina,Matya?ovsky, Ján,Maulide, Nuno,Merad, Jérémy,Pinto, Alexandre,Stopka, Tobias
, p. 7770 - 7774 (2021/06/16)
Isothiouronium salts are easily accessible and stable compounds. Herein, we report their use as versatile deoxasulfenylating agents enabling a stereoselective, thiol-free protocol for synthesis of thioethers from alcohols. The method is simple, scalable and tolerates a broad range of functional groups otherwise incompatible with other methods. Late-stage modification of several pharmaceuticals provides access to multiple analogues of biologically relevant molecules. Performed experiments give insight into the reaction mechanism.
Biomolecule interaction using atomic force microscope
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Page/Page column, (2014/03/26)
The present patent application describes a cantilever for atomic force microscopy (AFM), which includes a cantilever body having a fixed end and a free end, the free end having a surface region being chemically modified by a dendron in which a plurality of termini of the branched region of the dendron are bound to the surface, and a terminus of the linear region of the dendron is functionalized.
Method for preparing n-(γ(v)-bromoalkyl)phthalimides
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Page 3-4, (2008/06/13)
The invention concerns a procedure for preparation of N-(ω-bromoalkyl)phthalimides which consists of reacting potassium phthalimide with an α,ω-dibromoalkane without cosolvent, at a temperature from 50° C. to 130° C. by using a molar ratio of α,ω-dibromoalkane to potassium phthalimide from 2.5 to 6, then of removing excess α,ω-dibromoalkane, under reduced pressure at a temperature equal to 150° C. at most, of taking up the reaction medium again with a low boiling point alcohol at a temperature near that of the boiling point of said alcohol, of filtering at this temperature, of cooling the filtrate obtained and then of recovering the N-(ω-bromoalkyl)phthalimide.
