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4-BROMO-TOLUENE-3-SULFONYL CHLORIDE, with the chemical formula C7H6BrClO2S, is a sulfonyl chloride derivative known as p-toluenesulfonyl bromide. It is a colorless to light yellow liquid that is highly reactive and can cause severe skin and eye irritation. 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE is utilized in organic synthesis as a mild and selective oxidizing agent and a reagent for the preparation of sulfonamides.

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  • 141113-98-6 Structure
  • Basic information

    1. Product Name: 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE
    2. Synonyms: 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE;4-BROMO-TOLENE-3-SULFONYL CHLORIDE;2-BroMo-5-Methylbenzene-1-sulfonyl chloride
    3. CAS NO:141113-98-6
    4. Molecular Formula: C7H6BrClO2S
    5. Molecular Weight: 269.54
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 141113-98-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE(141113-98-6)
    11. EPA Substance Registry System: 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE(141113-98-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 141113-98-6(Hazardous Substances Data)

141113-98-6 Usage

Uses

Used in Pharmaceutical Industry:
4-BROMO-TOLUENE-3-SULFONYL CHLORIDE is used as a synthetic intermediate for the development of various drugs. Its mild and selective oxidizing properties make it a valuable component in the synthesis of pharmaceutical compounds, contributing to the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE is employed as a key ingredient in the production of pesticides. Its reactivity and ability to form sulfonamides facilitate the synthesis of effective pest control agents, enhancing crop protection and yield.
Used in Dye and Pigment Production:
4-BROMO-TOLUENE-3-SULFONYL CHLORIDE is used as a chemical intermediate in the manufacturing process of dyes and pigments. Its involvement in the synthesis of these colorants is crucial for producing a wide range of hues used in various industries, including textiles, plastics, and printing.
Used in Specialty Chemicals:
This sulfonyl chloride derivative is also utilized in the production of specialty chemicals, which are high-value compounds used in specific applications due to their unique properties. 4-BROMO-TOLUENE-3-SULFONYL CHLORIDE contributes to the development of these specialized products, expanding the capabilities and performance of various industrial processes.

Check Digit Verification of cas no

The CAS Registry Mumber 141113-98-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,1,1 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 141113-98:
(8*1)+(7*4)+(6*1)+(5*1)+(4*1)+(3*3)+(2*9)+(1*8)=86
86 % 10 = 6
So 141113-98-6 is a valid CAS Registry Number.

141113-98-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Bromo-5-methylbenzenesulfonyl chloride

1.2 Other means of identification

Product number -
Other names 4-Brom-toluol-3-sulfonylchlorid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:141113-98-6 SDS

141113-98-6Relevant articles and documents

A scaffold replacement approach towards new sirtuin 2 inhibitors

Seifert, Tina,Malo, Marcus,Kokkola, Tarja,Stéen, E. Johanna L.,Meinander, Kristian,Wallén, Erik A.A.,Jarho, Elina M.,Luthman, Kristina

, (2019/12/24)

Sirtuins (SIRT1–SIRT7) are an evolutionary conserved family of NAD+-dependent protein deacylases regulating the acylation state of ε-N-lysine residues of proteins thereby controlling key biological processes. Numerous studies have found association of the aberrant enzymatic activity of SIRTs with various diseases like diabetes, cancer and neurodegenerative disorders. Previously, we have shown that substituted 2-alkyl-chroman-4-one/chromone derivatives can serve as selective inhibitors of SIRT2 possessing an antiproliferative effect in two human cancer cell lines. In this study, we have explored the bioisosteric replacement of the chroman-4-one/chromone core structure with different less lipophilic bicyclic scaffolds to overcome problems associated to poor physiochemical properties due to a highly lipophilic substitution pattern required for achieve a good inhibitory effect. Various new derivatives based on the quinolin-4(1H)-one scaffold, bicyclic secondary sulfonamides or saccharins were synthesized and evaluated for their SIRT inhibitory effect. Among the evaluated scaffolds, the benzothiadiazine-1,1-dioxide-based compounds showed the highest SIRT2 inhibitory activity. Molecular modeling studies gave insight into the binding mode of the new scaffold-replacement analogues.

Biphenylsulfonyl-substituted imidazole derivatives, their preparation process, their use as a drug or diagnostic agent and drug containing them

-

Page column 18, (2008/06/13)

The invention relates to compounds of formula (I), wherein the symbols have the meanings indicated in the specification. The inventive compounds exhibit dramatic antiarrhythmic proprieties and contain a cardioprotective compound. They can preventively inhibit or strongly reduce pathophysiologic processes upon occurrence of ischemic injuries, especially ischemic cardiac arrhythmia. Said compounds also exhibit a strong inhibiting effect on cellular proliferation.

Biphenylsulfonyl cyanamides, method for the production thereof and their utilization as a medicament

-

, (2008/06/13)

The invention relates to compounds of the formula (I), in which the symbols have the following meaning: R(1) is 1. alkyl having 1, 2, 3, 4, 5, 6, 7 or 8 carbon atoms; 2. alkyl having 1, 2, 3, 4, 5, 6, 7 or 8 carbon atoms, in which one to all hydrogen atoms are replaced by fluorine; 3. alkenyl having 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 or 12 carbon atoms; or 4. —CnH2n?nn—Y, nn is zero or 2; and n is zero, 1, 2, 3 or 4; where n is unequal to zero or 1 if nn is equal to 2; 5. —CnH2n?nn—Y, nn is zero or 2; and n is 1, 2, 3 or 4; where n is unequal to 1 if nn is equal to 2.

Perfluoroalkyl-substituted, benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament containing them

-

, (2008/06/13)

Perfluoroalkyl-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and a medicament containing them A description is given of perfluoroalkyl-substituted benzoylguanidines of the formula I STR1 whe

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