Quinazoline antifolate thymidylate synthase inhibitors: Difluoro- substituted benzene ring analogues
The synthesis of a series of new C2-methyl-N10-alkylquinazoline-based thymidylate synthase (TS) inhibitors containing difluorinated p-aminobenzoate rings is described. Derivatives of the N10-propargyl and N10- m
Thornton,Jackman,Marsham,O'Connor,Bishop,Calvert
p. 2321 - 2327
(2007/10/02)
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