141468-55-5 Usage
Uses
Used in Pharmaceutical Industry:
BOC-VAL-NCA is used as a reagent for the preparation of N-protected valine derivatives for the production of various functional materials and pharmaceuticals.
Used in Peptide Chemistry Research and Manufacturing:
BOC-VAL-NCA is used as a coupling reagent in solid-phase peptide synthesis to introduce valine into peptide chains, due to its ability to form stable and reactive derivatives under mild conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 141468-55-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,4,6 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 141468-55:
(8*1)+(7*4)+(6*1)+(5*4)+(4*6)+(3*8)+(2*5)+(1*5)=125
125 % 10 = 5
So 141468-55-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO5/c1-6(2)7-8(13)16-9(14)12(7)10(15)17-11(3,4)5/h6-7H,1-5H3/t7-/m0/s1
141468-55-5Relevant articles and documents
Method of obtaining urethane-protected n-carboxyanhydrides of alpha amino acids
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Page/Page column 3-4, (2008/06/13)
The invention relates to a method of preparing urethane-protected N-carboxyanhydrides of alpha amino acids. The inventive method enables the synthesis of urethane-protected N-carboxyanhydrides of alpha amino acids in the presence of a catalytic quantity of triethylene diamine without the addition of a tertiary amine-type base.
N-Alkoxycarbonyl Amino Acid N-Carboxyanhydrides and N,N-Dialkoxycarbonyl Amino Acid Fluorides from N,N-Diprotected Amino Acids
Savrda, J.,Wakselman, M.
, p. 812 - 813 (2007/10/02)
Activation of N,N-bis-Boc or N-Boc N-Z amino acids with SOCl2-DMF leads to N-protected N-carboxy amino acid anhydrides, whereas treatment with cyanuric fluoride at low temperature gives mainly N,N-bis-protected amino acid fluorides, which are efficient ac