141511-19-5Relevant articles and documents
Synthesis and pharmacological study of butyric derivatives in piperazinic series
Pieri,Sefraoui,Arnould-Guerin,Kirkiacharian,Cheav
, p. 119 - 123 (2007/10/02)
The pharmacological study of butyric derivative in piperazinic series indicate an activity on central nervous system, particularly the 4-butanoyl-1-(3-chlorophenyl) piperazine.
Structure-activity relationship studies of central nervous system agents. 5. Effect of the hydrocarbon chain on the affinity of 4-substituted 1-(3- chlorophenyl)piperazines for 5-HT(1A) receptor site
Mokrosz,Pietrasiewicz,Duszynska,Cegla
, p. 2369 - 2374 (2007/10/02)
The effect of the hydrocarbon chain of the model 4-substituted 1-(3- chlorophenyl)piperazines 12-31 on their affinity for 5-HT(1A) receptor sites was investigated. It was found that elongation of the 4-n-alkyl chain strongly increases the 5-HT(1A) affinit