141998-21-2

Basic information

• Product Name: Acetamide, N-[2-[[2-[(2-aminoethyl)amino]ethyl]amino]ethyl]-
• Synonyms: Acetamide, N-[2-[[2-[(2-aminoethyl)amino]ethyl]amino]ethyl]-;N1-Acetyl TriethylenetetraMine;N1-Acetyl TriethylenetetraMine Trihydrochloride
• CAS NO: 141998-21-2
• Molecular Formula: C8H20N4O
• Molecular Weight: 188.27
• Product Categories: Aliphatics;Amines;Chelating Agents & Ligands;Metabolites & Impurities;Aliphatics, Amines, Chelating Agents & Ligands, Metabolites & Impurities
• Mol File: 141998-21-2.mol

Chemical Properties

• Boiling Point: 401.5±30.0 °C(Predicted)
• Appearance: /
• Density: 1.002±0.06 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: Water (Slightly)
• PKA: 16.15±0.46(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: Acetamide, N-[2-[[2-[(2-aminoethyl)amino]ethyl]amino]ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-[2-[[2-[(2-aminoethyl)amino]ethyl]amino]ethyl]-(141998-21-2)
• EPA Substance Registry System: Acetamide, N-[2-[[2-[(2-aminoethyl)amino]ethyl]amino]ethyl]-(141998-21-2)

Safety Data

• Hazardous Substances Data: 141998-21-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Acetamide, N-[2-[[2-[(2-aminoethyl)amino]ethyl]amino]ethyl]is used as a chelating agent for the selective binding and sequestration of copper ions (CuII). This application is particularly relevant in the treatment of conditions related to copper imbalance or toxicity, as it can help regulate copper levels in the body and mitigate the associated symptoms.
Used in Research and Development:
In the field of research and development, Acetamide, N-[2-[[2-[(2-aminoethyl)amino]ethyl]amino]ethyl]can be utilized as a starting material or intermediate for the synthesis of more complex molecules with potential therapeutic or diagnostic applications. Its unique structure and copper-binding properties make it an interesting candidate for the development of new drugs or imaging agents.
Used in Environmental Applications:
Acetamide, N-[2-[[2-[(2-aminoethyl)amino]ethyl]amino]ethyl]may also find use in environmental applications, such as the removal of copper ions from contaminated water or soil. Its chelating properties can be harnessed to selectively bind and remove copper ions, thus reducing the environmental impact of copper pollution.

Upstream product

• 112-24-3 triethylentetramine 
• 604-68-2 α-D-glucopyranose peracetylate 

Relevant articles and documents

The number and distances of positive charges of polyamine side chains in a series of perylene diimides significantly influence their ability to induce G-quadruplex structures and inhibit human telomerase

We have synthesized eight polyamine perylene diimides to conjugate the efficiency of perylene derivatives in stabilizing G-quadruplex structures and the polyamines' biological activity, due to specific interactions with different DNA domains. Our study was carried out by investigating the ability of these derivatives to induce inter- and intramolecular G-quadruplex structures by polyacrylamide gel electrophoresis (PAGE) and to inhibit telomerase in a modified TRAP assay. The two properties appear to be satisfactorily correlated and they show that the number and distances of positive charges in the side chains dramatically influence both these features. Although our previous studies on perylene derivatives with mono-positively charged side chains indicated that self assembly in aqueous solution leads to a major efficiency, the result observed with the spermine derivative suggests that a too strong aggregation is unfavourable, because it determines a lower solubility of the compounds.

Regiospecific synthesis of mono- or diacetylated polyethylenepolyamine derivatives

Acetylated polyethylenepolyamines CH3CONHCH2(CH2-NH-CH2)(n)CH2NH2 (n = 1,2;) were synthesized using α-D-pentaacetyl-glucose as an acetylating agent.