- An efficient CuI/DBU-catalyzed one-pot protocol for synthesis of 1,4-disubstituted 1,2,3-triazoles
-
A convenient CuI/DBU catalyzed one-pot method has been developed for the synthesis of 1,4-disubstituted 1,2,3-triazoles through the coupling of aryl iodides with sodium azide, followed by the intermolecular cyclization between the generated aryl azides and phenylacetaldehyde derivatives or alkynes in DMSO. The established protocol was compatible with a wide scope of substrates in good to excellent yields.
- Jiang, Yuqin,Li, Xingfeng,Zhao, Yaru,Jia, Shuhong,Li, Mingrui,Zhao, Zhiqi,Zhang, Ruili,Li, Wei,Zhang, Weiwei
-
p. 110102 - 110107
(2016)
-
Read Online
- Aqueous bile salt accelerated cascade synthesis of 1,2,3-triazoles from arylboronic acids
-
A facile, efficient and mild copper catalyzed strategy for cascade synthesis of various 1,4-disubstituted 1,2,3-triazoles from arylboronic acids, sodium azide and alkynes was developed by using aqueous bile salt NaDC solution as an accelerating medium. Lo
- Garg, Anirban,Ali, Abdul Aziz,Damarla, Krishnaiah,Kumar, Arvind,Sarma, Diganta
-
supporting information
p. 4031 - 4035
(2018/10/09)
-
- Copper-mediated synthesis of 1,2,3-triazoles from N-tosylhydrazones and anilines
-
NNNifty targets: In a straightforward copper-mediated synthesis of 1,4-disubstituted and 1,4,5-trisubstituted 1,2,3-triazoles, readily available aniline and N-tosylhydrazone substrates underwent cyclization through Ci£N and Ni£N bond formation (see scheme
- Chen, Zhengkai,Yan, Qiangqiang,Liu, Zhanxiang,Xu, Yiming,Zhang, Yuhong
-
p. 13324 - 13328
(2014/01/06)
-
- Magnetically recoverable CuFe2O4 nanoparticles: Catalyzed synthesis of aryl azides and 1,4-diaryl-1,2,3-triazoles from boronic acids in water
-
Magnetically recoverable and reusable CuFe2O4 nanoparticles are shown to be highly efficient catalysts for the one-pot synthesis of biologically important 1,4-diaryl-1,2,3-triazoles starting from boronic acids, sodium azide, and acetylenes. The use of aqueous reaction medium at room temperature, the low cost and facile recovery of the catalyst by application of an external magnetic field, and consistently high catalytic efficiency for at least three consecutive cycles renders the protocol operationally attractive. Magnetic and catalytically competent CuFe 2O4 nanoparticles proved to be highly efficient in the three-component synthesis of 1,4-diaryl-1,2,3-triazoles, a class of compounds that has been recognized for its anticancer activity. Copyright
- Kumar, A. Suresh,Reddy, M. Amarnath,Knorn,Reiser,Sreedhar
-
p. 4674 - 4680
(2013/07/26)
-