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142139-60-4

Lapisteride, a benzofuran derivative, is a potent and selective inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5), an enzyme involved in the biosynthesis of androgens. It has been studied as a potential treatment for androgen-dependent conditions such as prostate cancer and androgenic alopecia, showing promising results in preclinical studies.
Used in Pharmaceutical Industry:
Lapisteride is used as a therapeutic agent for androgen-dependent conditions such as prostate cancer and androgenic alopecia. Its ability to inhibit androgen production and activity makes it a promising candidate for the treatment of various androgen-related disorders.
However, more research and clinical trials are needed to fully understand its efficacy and safety profile.

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  • 1H-Indeno[5,4-f]quinoline-7-carboxamide,2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-N-[1-(4-methoxyphenyl)-1-methylethyl]-4a,6a-dimethyl-2-oxo-,(4aR,4bS,6aS,7S,9aS,9bS,11aR)-

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  • 1H-Indeno[5,4-f]quinoline-7-carboxamide,2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-N-[1-(4-methoxyphenyl)-1-methylethyl]-4a,6a-dimethyl-2-oxo-,(4aR,4bS,6aS,7S,9aS,9bS,11aR)-

    Cas No: 142139-60-4

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  • 1H-Indeno[5,4-f]quinoline-7-carboxamide,2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-N-[1-(4-methoxyphenyl)-1-methylethyl]-4a,6a-dimethyl-2-oxo-,(4aR,4bS,6aS,7S,9aS,9bS,11aR)-

    Cas No: 142139-60-4

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  • 142139-60-4 Structure

  • Basic information

    1. Product Name: LAPISTERIDE
    2. Synonyms: LAPISTERIDE
    3. CAS NO:142139-60-4
    4. Molecular Formula: C29H40N2O3
    5. Molecular Weight: 464.646
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 142139-60-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: LAPISTERIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: LAPISTERIDE(142139-60-4)
    11. EPA Substance Registry System: LAPISTERIDE(142139-60-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 142139-60-4(Hazardous Substances Data)

142139-60-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 142139-60-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,1,3 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 142139-60:
(8*1)+(7*4)+(6*2)+(5*1)+(4*3)+(3*9)+(2*6)+(1*0)=104
104 % 10 = 4
So 142139-60-4 is a valid CAS Registry Number.

142139-60-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2-(4-methoxyphenyl)propan-2-yl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

1.2 Other means of identification

Product number -
Other names UNII-T50SJ23G82

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:142139-60-4 SDS

142139-60-4Downstream Products

142139-60-4Relevant articles and documents

Method for treating prostate cancer

-

, (2008/06/13)

A method for treatment or prevention of prostate cancer by administering an effective amount of a compound of the formula (I) or a pharmaceutically acceptable salt or ester thereof. In formula (I) (which follows), each of R1 and R2 is a hydrogen atom, a h

Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use

-

, (2008/06/13)

Compounds of formula (I): STR1 (in which: R1 is a hydrogen atom, an unsubstituted alkyl group, an aryl-substituted alkyl group or a heterocyclic-substituted alkyl group; R2 is an aryl-substituted alkyl group, a heterocyclic-substitut

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