142172-51-8

Basic information

• Product Name: 2-(4-BROMOBUTYL)-1 3 2-BENZODIOXABOROLE&
• Synonyms: 4-Bromo-1-butylboronic acid catechol ester, 96%;2-(4-BroMobutyl)benzo[d][1,3,2]dioxaborole;4-Bromo-1-butylboronic acid catechol ester 96%
• CAS NO: 142172-51-8
• Molecular Formula: C₁₀H₁₂BBrO₂
• Molecular Weight: 254.92
• Mol File: 142172-51-8.mol

Chemical Properties

• Boiling Point: 301.9°C at 760 mmHg
• Flash Point: 221 °F
• Appearance: /
• Density: 1.38g/cm³
• Vapor Pressure: 0.00183mmHg at 25°C
• Refractive Index: n20/D 1.5362(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(4-BROMOBUTYL)-1 3 2-BENZODIOXABOROLE&(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-BROMOBUTYL)-1 3 2-BENZODIOXABOROLE&(142172-51-8)
• EPA Substance Registry System: 2-(4-BROMOBUTYL)-1 3 2-BENZODIOXABOROLE&(142172-51-8)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 142172-51-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-BROMOBUTYL)-1 3 2-BENZODIOXABOROLE& is used as a precursor in the development of new pharmaceuticals due to its unique chemical structure and potential for medicinal applications.
Used in Antifungal Treatments:
In the field of Antifungal Medicine, 2-(4-BROMOBUTYL)-1 3 2-BENZODIOXABOROLE& is utilized for its antifungal properties, offering a potential solution for treating drug-resistant fungal infections.
Used in Organic Synthesis:
2-(4-BROMOBUTYL)-1 3 2-BENZODIOXABOROLE& is employed as a reagent in organic synthesis, contributing to the creation of various organic compounds.
Used in Borylation Reactions:
Within the realm of Chemical Synthesis, 2-(4-BROMOBUTYL)-1 3 2-BENZODIOXABOROLE& is used as a borylating agent, facilitating specific types of chemical reactions that are important for the synthesis of complex organic molecules.

InChI:InChI=1/C10H12BBrO2/c12-8-4-3-7-11-13-9-5-1-2-6-10(9)14-11/h1-2,5-6H,3-4,7-8H2

Upstream product

• 13826-27-2 2,2'-bis(1,3,2-benzodioxaborole) 
• 5162-44-7 1-bromo-4-butene 
• 274-07-7 benzo[1,3,2]dioxaborole 

Downstream Products

• 13633-25-5 1-Bromo-4-phenylbutane 
• 124215-50-5 2-(4-bromobutyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 

Relevant articles and documents

Photoinduced decarboxylative borylation of carboxylic acids

The conversion of widely available carboxylic acids into versatile boronic esters would be highly enabling for synthesis. We found that this transformation can be effected by illuminating the N-hydroxyphthalimide ester derivative of the carboxylic acid under visible light at room temperature in the presence of the diboron reagent bis(catecholato)diboron. A simple workup allows isolation of the pinacol boronic ester. Experimental evidence suggests that boryl radical intermediates are involved in the process. The methodology is illustrated by the transformation of primary, secondary, and tertiary alkyl carboxylic acids as well as a diverse range of natural-product carboxylic acids, thereby demonstrating its broad utility and functional group tolerance.

Synthesis of novel prostaglandins containing a boronate in the α chain

A novel class of prostaglandins containing a boronate in the α chain have been synthesized. The key steps in the synthesis were the preparation of the ylide containing the boronate and the subsequent Wittig reaction using the ylide. (C) 2000 Elsevier Scie