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1422156-20-4

C20H19FN2O3 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1422156-20-4 Structure

  • Basic information

    1. Product Name: C20H19FN2O3
    2. Synonyms: C20H19FN2O3
    3. CAS NO:1422156-20-4
    4. Molecular Formula:
    5. Molecular Weight: 354.381
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1422156-20-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C20H19FN2O3(CAS DataBase Reference)
    10. NIST Chemistry Reference: C20H19FN2O3(1422156-20-4)
    11. EPA Substance Registry System: C20H19FN2O3(1422156-20-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1422156-20-4(Hazardous Substances Data)

1422156-20-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1422156-20-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,2,1,5 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1422156-20:
(9*1)+(8*4)+(7*2)+(6*2)+(5*1)+(4*5)+(3*6)+(2*2)+(1*0)=114
114 % 10 = 4
So 1422156-20-4 is a valid CAS Registry Number.

1422156-20-4Downstream Products

1422156-20-4Relevant articles and documents

Synthesis, biological evaluation, 3D-QSAR studies of novel aryl-2H-pyrazole derivatives as telomerase inhibitors

Luo, Yin,Zhang, Shuai,Qiu, Ke-Ming,Liu, Zhi-Jun,Yang, Yu-Shun,Fu, Jie,Zhong, Wei-Qing,Zhu, Hai-Liang

, p. 1091 - 1095 (2013/03/13)

A series of novel aryl-2H-pyrazole derivatives bearing 1,4-benzodioxan or 1,3-benzodioxole moiety were designed as potential telomerase inhibitors to enhance the ability of aryl-2H-pyrazole derivatives to inhibit telomerase, a target of anticancer. The telomerase inhibition tests showed that compound 16A displayed the most potent inhibitory activity with IC50 value of 0.9 μM for telomerase. The antiproliferative tests showed that compound 16A exhibited high activity against human gastric cancer cell SGC-7901 and human melanoma cell B16-F10 with IC50 values of 18.07 and 5.34 μM, respectively. Docking simulation showed that compound 16A could bind well with the telomerase active site and act as telomerase inhibitor. 3D-QSAR model was also built to provide more pharmacophore understanding that could be used to design new agents with more potent telomerase inhibitory activity.

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