142670-86-8Relevant articles and documents
COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES
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Page/Page column 127; 128, (2014/06/11)
The present invention provides compounds of formula I: [INSERT FORMULA HERE] or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. The present invention further provides pharmaceutical compositions comprising such compounds and methods of using such compounds for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease, such as malaria, caused by a Plasmodium parasite.
SYNTHESE DE N-ALKYL-3-ARYL-2-DIPHENYLPHOSPHINOYL-1H-PYRIDOTHIAZINES
Couture, Axel,Deniau, Eric,Crandclaudon, Pierre
, p. 91 - 98 (2007/10/02)
A variete of N-alkyl-3-aryl-2-diphenylphosphinoyl-1H-pyridothiazines has been efficiently synthesized by treatment of the anion of 3-(N-alkyl-N-diphenylphosphinoylmethylamino)-2-chloro or -2,6-dichloropyridines with the appropriate aromatic O-