1427174-96-6Relevant articles and documents
Suzuki-miyaura cross-coupling of potassium dioxolanylethyltrifluoroborate and aryl/heteroaryl chlorides
Fleury-Bregeot, Nicolas,Oehlrich, Daniel,Rombouts, Frederik,Molander, Gary A.
, p. 1536 - 1539 (2013/06/26)
A robust and efficient protocol for the introduction of the dioxolanylethyl moiety onto various aryl and heteroaryl halides has been developed, providing cross-coupling yields up to 93%. Copper-catalyzed borylation of 2-(2-bromoethyl)-1,3-dioxolane with bis(pinacolato)diboron followed by treatment with potassium bifluoride provides the key organotrifluoroborate reagent.