142978-18-5

Basic information

• Product Name: 9-(2-CARBOXY-2-CYANOVINYL)JULOLIDINE
• Synonyms: CCVJ;9-(2-CARBOXY-2-CYANOVINYL)JULOLIDINE;9-((E)-2-carboxy-2-cyanovinyl)*julolidine;9-((E)-2-CARBOXY-2-CYANOVINYL) &;9-[(2-Cyano-2-hydroxycarbonyl)-vinyl]-julolidine;-(2-CARBOXY-2-CYANOVINYL)JULOLIDINE;CCVJ [9-(2-Carboxy-2-cyanovinyl)julolidine];1,5-dihydropyrido[3,2,1-ij]quinoline acrylate
• CAS NO: 142978-18-5
• Molecular Formula: C16H16N2O2
• Molecular Weight: 268.31
• Mol File: 142978-18-5.mol

Chemical Properties

• Boiling Point: 539.4°C at 760 mmHg
• Flash Point: 280°C
• Appearance: /
• Density: 1.32g/cm³
• Vapor Pressure: 1.81E-12mmHg at 25°C
• Refractive Index: 1.65
• Storage Temp.: 2-8°C
• Solubility: DMSO: soluble
• CAS DataBase Reference: 9-(2-CARBOXY-2-CYANOVINYL)JULOLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(2-CARBOXY-2-CYANOVINYL)JULOLIDINE(142978-18-5)
• EPA Substance Registry System: 9-(2-CARBOXY-2-CYANOVINYL)JULOLIDINE(142978-18-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 142978-18-5(Hazardous Substances Data)

Usage

Uses

Used in Research Applications:
9-(2-CARBOXY-2-CYANOVINYL)JULOLIDINE is used as a fluorescent probe for binding to proteins, allowing researchers to study protein interactions and conformational changes with high sensitivity and specificity. Its fluorescence properties enable real-time monitoring of these processes, providing valuable insights into protein dynamics and function.
Used in the Study of Actin:
In the field of cell biology, 9-(2-CARBOXY-2-CYANOVINYL)JULOLIDINE is used as a fluorescent molecular rotor for investigating the G-F transformation of actin, a crucial process in cell motility and structure. By monitoring the fluorescence changes of this molecule, researchers can gain a better understanding of the molecular mechanisms underlying actin polymerization and depolymerization, which are essential for various cellular processes.

InChI:InChI=1/C16H16N2O2/c17-10-14(16(19)20)9-11-7-12-3-1-5-18-6-2-4-13(8-11)15(12)18/h7-9H,1-6H2,(H,19,20)/b14-9+

Upstream product

• 33985-71-6 9-julolidinecarboxaldehyde 
• 372-09-8 cyanoacetic acid 

Relevant articles and documents

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FLUORESCENT MOLECULAR ROTORS

The present invention relates to methods and compositions for detecting an interaction between a protein and a ligand, comprising: (i) binding at least one fluorescent molecular rotor to said ligand or protein; and (ii) detecting a change in fluorescence emitted by said fluorescent molecular rotor after contact of the bound fluorescent molecular rotor with the other of said ligand or protein, thereby detecting an interaction between the ligand and the protein, wherein the fluorescent molecular rotor comprises: a rotating ?-bond; an electron-donating moiety; an electron-accepting moiety; and a ?-conjugated linker.