cas 142994-05-6, 2-Methylthio-4-trifluoromethylbenzoic acid

Articles about 142994-05-6Total 10 be found

Synthesis method of 2-methylsulfonyl-4-trifluoromethyl benzoic acid
The invention belongs to the field of preparation of pesticide intermediates, and particularly relates to a synthesis method of an intermediate 2-methylsulfonyl-4-trifluoromethyl benzoic acid for preparing important pesticides such as sulfonyl pyrazole an
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Paragraph 0034-0036; 0038-0040

(2020/12/14)

CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS
The present invention relates to the use of a compound of formula I wherein R1, R2, R3, R4, X and n are as defined herein or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomers and/or optical isomers for the treatment of psychoses, pain, dysfunction in memory and learning, attention deficit, schizophrenia, dementia disorders or Alzheimer's disease.
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Page/Page column 13

(2011/04/14)

CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS
The present invention relates to the use of a compound of general formula (I) wherein R1/R2 are independently from each other hydrogen, lower alkyl, -CH2)o-cycloalkyl for o being 0 or 1, or are benzyl or heterocycloalkyl; or R1 and R2 are together with the N-atom to which they are attached a ring containing -(CH2)3-, -(CH2)4-, -(CH2)5-, -(CH2)2-O-(CH2)2-, -(CH2)2-S-(CH2)2-, -(CH2)2-NR-(CH2)2-, -(CH2)2-C(O)-(CH2)2-, -(CH2)2-CF2-(CH2)2-, -CH2-CHR-(CH2)2, -CHR-(CH2)3, CHR-(CH2)2-CHR-, or is the ring 2,6-diaza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester and R is hydroxy, halogen, cycloalkyl, or C(O)O-lower alkyl; X is -(CH2)4-, -(CH2)3-, -(CH2)2- or -CH2-; R3 is S-lower alkyl, CF3, OCHF2, lower alkoxy, lower alkyl, phenyl, cycloalkyl or halogen; R4 is CF3, lower alkoxy, lower alkyl, halogen and n is 1 or 2; or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomers and/or optical isomers thereof for the manufacture of a medicament for the treatment of psychoses, pain, dysfunction in memory and learning, attention deficit, schizophrenia, dementia disorders or Alzheimer's disease.
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Page/Page column 23

(2011/04/14)

GlyT1 RECEPTOR ANTAGONISTS
The present invention relates to a compound of formula I wherein R1, R2, X, Ar1 and Ar2 are as defined herein and to pharmaceutically acceptable acid addition salts, to a racemic mixtures, or to their correspond
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Page/Page column 8

(2010/03/31)

PROCESS FOR THE PREPARATION OF 2-ALKYLTHIO BENZOIC ACID DERIVATIVES
A process for preparing a compound of the formula comprising reacting a compound of the formula wherein R3 is nitro or halo, or a salt thereof, with a compound of the formula R1SX (III) wherein X is hydrogen or alkali metal.
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(2008/06/13)

Herbicidal 2-cyano-1,3-diones
Herbicides derived from 2-cyano-1,3-diones have the formula: STR1 wherein R, R1, R2 R3, R4 and R5 are as defined in the description. The compounds are intended for use pre- and post-emergence as selective herbicides in maize and a large number of other monocotyledon crops.
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(2008/06/13)

Herbicidal 4-acyl-5-aryl isoxazole derivatives
5-Aryl isoxazole derivatives of formula (I): STR1 wherein: Ar represents phenyl optionally substituted substituted by one or more groups R2 ; R represents hydrogen, --CO2 R3, --COR4, cyano, halogen, alkyl or hal
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(2008/06/13)

4-Benzoylisoxazole derivatives and their use as herbicides
4-Benzoyl isoxazole derivatives of general formula (I): wherein:, R1 represents cyclopropyl;, R2 represents -S(O)nR;, R3 represents chlorine, bromine or trifluoromethyl;, R represents methyl; and, n represents 2;, and their use as herbicides is
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(2008/06/13)

4 Benzoyl isoxazole derivatives
4-Benzoyl isoxazole derivatives of the formula I: wherein:, R represents alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, optionally substituted cycloalkyl, -CO2R3,-COR5,cyano,nitro, -CONR31R4 or a halogen atom;, R1 represents :-, hydrogen , alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl or optionally substituted cycloalkyl, R2 represents :-, halogen, R5, -SR5, -SOR5, -SO2R5, -SO2NR31R4,-CO2R3, -COR5, -CONR31R4, -CSNR31R4, -OR5, a nitro group, a cyano group, a group -O(CH2)q-OR5 or alkyl substituted by OR5;, R3, R31 and R4, which may be the same or different, each represents:-, hydrogen, alkyl or haloalkyl;, R5 represents alkyl or haloalkyl;, n represents an integer from 1 to 5; and, q represents an integer from 1 to 3;, and agriculturally acceptable salts thereof and their use as herbicides is described.
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(2008/06/13)

2-Cyano-1,3-dione herbicides
Compounds of formula: wherein:, R represent an optionally substituted alkyl or an optionally substituted cycloalkyl group;, R1 represents halogen, hydrogen, nitro, -O(CH2)mOR5, cyano, -SR5, R5, OR5, CO2R5 or alkyl substituted by OR5;, R2 and R3 represent a halogen, hydrogen, R5, alkyl substituted by -OR5, -O(CH2)mOR5, nitro, cyano, -OR5 or -CO2R5;, R4 and R5 represent an optionally substituted alkyl group;, n represents zero, 1 or 2 and, m represents an integer from 1 to 3;, and agriculturally acceptable salts of enolic tautomeric forms thereof are useful as herbicides.
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(2008/06/13)