142994-05-6

Basic information

• Product Name: 2-Methylthio-4-trifluoromethylbenzoic acid
• CAS NO: 142994-05-6
• Molecular Formula: C₉H₇F₃O₂S
• Molecular Weight: 236.215
• Mol File: 142994-05-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 284.648 °C at 760 mmHg
• Flash Point: 125.951 °C
• Density: 1.447 g/cm³
• CAS DataBase Reference: 2-Methylthio-4-trifluoromethylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methylthio-4-trifluoromethylbenzoic acid(142994-05-6)
• EPA Substance Registry System: 2-Methylthio-4-trifluoromethylbenzoic acid(142994-05-6)

Safety Data

• Hazardous Substances Data: 142994-05-6(Hazardous Substances Data)

Usage

General Description

2-Methylthio-4-trifluoromethylbenzoic acid is a chemical compound with the molecular formula C10H7F3O2S. It is a derivative of benzoic acid and contains a methylthio group and a trifluoromethyl group. 2-Methylthio-4-trifluoromethylbenzoic acid is commonly used in the synthesis of pharmaceuticals and agrochemicals. It exhibits a wide range of biological activities and has been studied for its potential anti-inflammatory, antibacterial, and antifungal properties. Additionally, it has been investigated for its potential use as a building block in organic synthesis and drug development. Overall, 2-Methylthio-4-trifluoromethylbenzoic acid is a versatile and important chemical with various applications in the fields of medicine and agriculture.

Upstream product

• 161462-33-5 1-cyano-2-methylthio-4-trifluoromethylbenzene 
• 109-72-8 n-butyllithium 
• 142994-07-8 1-bromo-2-methylsulfanyl-4-(trifluoromethyl)benzene 
• 219684-56-7 2-chloro-4-trifluoromethylbenzoic acid sodium salt 

Downstream Products

• 142994-06-7 2-(methylsulphonyl)-4-trifluoromethylbenzoic acid 

Relevant articles and documents

Synthesis method of 2-methylsulfonyl-4-trifluoromethyl benzoic acid

The invention belongs to the field of preparation of pesticide intermediates, and particularly relates to a synthesis method of an intermediate 2-methylsulfonyl-4-trifluoromethyl benzoic acid for preparing important pesticides such as sulfonyl pyrazole an

CARBOCYCLIC GLYT1 RECEPTOR ANTAGONISTS

The present invention relates to the use of a compound of general formula (I) wherein R1/R2 are independently from each other hydrogen, lower alkyl, -CH2)o-cycloalkyl for o being 0 or 1, or are benzyl or heterocycloalkyl; or R1 and R2 are together with the N-atom to which they are attached a ring containing -(CH2)3-, -(CH2)4-, -(CH2)5-, -(CH2)2-O-(CH2)2-, -(CH2)2-S-(CH2)2-, -(CH2)2-NR-(CH2)2-, -(CH2)2-C(O)-(CH2)2-, -(CH2)2-CF2-(CH2)2-, -CH2-CHR-(CH2)2, -CHR-(CH2)3, CHR-(CH2)2-CHR-, or is the ring 2,6-diaza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester and R is hydroxy, halogen, cycloalkyl, or C(O)O-lower alkyl; X is -(CH2)4-, -(CH2)3-, -(CH2)2- or -CH2-; R3 is S-lower alkyl, CF3, OCHF2, lower alkoxy, lower alkyl, phenyl, cycloalkyl or halogen; R4 is CF3, lower alkoxy, lower alkyl, halogen and n is 1 or 2; or to a pharmaceutically acceptable acid addition salt, to a racemic mixture, or to its corresponding enantiomers and/or optical isomers thereof for the manufacture of a medicament for the treatment of psychoses, pain, dysfunction in memory and learning, attention deficit, schizophrenia, dementia disorders or Alzheimer's disease.

PROCESS FOR THE PREPARATION OF 2-ALKYLTHIO BENZOIC ACID DERIVATIVES

A process for preparing a compound of the formula comprising reacting a compound of the formula wherein R3 is nitro or halo, or a salt thereof, with a compound of the formula R1SX (III) wherein X is hydrogen or alkali metal.