143225-28-9

Basic information

• Product Name: Butanedioic acid, methyl-, 1-(phenylmethyl) ester, (2R)- (9CI)
• Synonyms: Butanedioic acid, methyl-, 1-(phenylmethyl) ester, (2R)- (9CI);(2R)-Methylbutanedioic acid 1-(phenylmethyl) ester;(R)-Methylbutanedioic acid 1-(phenylmethyl) ester
• CAS NO: 143225-28-9
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.23716
• Product Categories: ACIDHALIDE
• Mol File: 143225-28-9.mol

Chemical Properties

• Appearance: /
• Density: 1.189
• CAS DataBase Reference: Butanedioic acid, methyl-, 1-(phenylmethyl) ester, (2R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Butanedioic acid, methyl-, 1-(phenylmethyl) ester, (2R)- (9CI)(143225-28-9)
• EPA Substance Registry System: Butanedioic acid, methyl-, 1-(phenylmethyl) ester, (2R)- (9CI)(143225-28-9)

Safety Data

• Hazardous Substances Data: 143225-28-9(Hazardous Substances Data)

Upstream product

• 147649-95-4 (R)-2-Methyl-4-pentenoic acid phenylmethyl ester 

Relevant articles and documents

Sensing remote chirality: Stereochemical determination of β-, γ-, and δ-chiral carboxylic acids

Determining the absolute stereochemisty of small molecules bearing remote nonfunctionalizable stereocenters is a challenging task. Presented is a solution in which appropriately substituted bis(porphyrin) tweezers are used. Complexation of a suitably derivatized β-, γ-, or δ-chiral carboxylic acid to the tweezer induces a predictable helicity of the bis(porphyrin), which is detected as a bisignate Cotton Effect (ECCD). The sign of the ECCD curve is correlated with the absolute stereochemistry of the substrate based on the derived working mnemonics in a predictable manner.

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