143317-74-2 Usage
Uses
Used in Pharmaceutical Industry:
Erucylphosphocholine is used as an anticancer agent for its ability to induce apoptosis in cancer cells. It is particularly effective against solid malignancies such as pancreatic and colorectal cancers, disrupting the cell membrane and altering lipid metabolism to cause cancer cell death.
Used in Anti-inflammatory Applications:
Erucylphosphocholine is used as an anti-inflammatory agent for its potential role in reducing inflammation in conditions such as arthritis. Further research is needed to fully understand its mechanisms of action and therapeutic uses in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 143317-74-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,3,1 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 143317-74:
(8*1)+(7*4)+(6*3)+(5*3)+(4*1)+(3*7)+(2*7)+(1*4)=112
112 % 10 = 2
So 143317-74-2 is a valid CAS Registry Number.
InChI:InChI=1/C27H56NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-26-31-33(29,30)32-27-25-28(2,3)4/h12-13H,5-11,14-27H2,1-4H3/b13-12-
143317-74-2Relevant articles and documents
Antitumor phospholipids: A one-pot introduction of a phosphocholine moiety into lipid hydroxy acceptors
Erukulla, Ravi Kumar,Byun, Hoe-Sup,Bittman, Robert
, p. 5783 - 5784 (1994)
A high-yielding, 3-step, one-pot conversion of lipid hydroxy acceptors 2 into clinically useful alkylphosphocholines 1 is reported. Reaction of 2 with ethylene chlorophosphite gave phosphite 3, which underwent oxidation and ring opening with bromine in CH2Cl2 to give (2-bromoethyl)phosphate ester 4; hydrolysis of the P-Br bond and quaternization of 4 with aqueous trimethylamine generated 1.
Novel alkyl phospholipid derivatives and uses thereof
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Page/Page column 60, (2010/11/27)
The present invention provides novel alkyl phospholipid derivatives that are useful for treating various diseases including tumors and/or pathophysiological conditions in mammals, preferably humans, that are caused by microorganisms, in particular fungi, protozoa, bacteria and/or viruses. Such alkyl phospholipids can be employed as single drugs or in the course of combination therapies, in particular for the treatment of leishmaniasis, trypanosomiasis and/or malaria.
