143330-91-0

Basic information

• Product Name: 3,5-DIHYDROXYBENZOIC ACID 2,2,2-TRICHLOROETHYL ESTER
• Synonyms: 2,2,2-TRICHLOROETHYL 3,5-DIHYDROXYBENZOATE;ALPHA-RESORCYLIC ACID 2,2,2-TRICHLOROETHYL ESTER;3,5-DIHYDROXYBENZOIC ACID 2,2,2-TRICHLOROETHYL ESTER;Ca.20%indichloromethane;3,5-DIHYDROXYBENZOIC ACID 2,2,2-TRICHLOROETHYL ESTER: (CA. 20% IN DICHLOROMETHANE);2,2,2-Trichloroethyl 3,5-Dihydroxybenzoate (ca. 20% in Dichloromethane, ca. 1mol/L);3,5-Dihydroxybenzoic Acid 2,2,2-Trichloroethyl Ester alpha-Resorcylic Acid 2,2,2-Trichloroethyl Ester
• CAS NO: 143330-91-0
• Molecular Formula: C₉H₇Cl₃O₄
• Molecular Weight: 285.51
• Product Categories: Building Blocks for Dendrimers;Functional Materials
• Mol File: 143330-91-0.mol

Chemical Properties

• Boiling Point: 447.3°C at 760 mmHg
• Flash Point: 224.3°C
• Appearance: /
• Density: 1.632g/cm³
• Vapor Pressure: 1.29E-08mmHg at 25°C
• Refractive Index: 1.613
• Storage Temp.: Refrigerator
• CAS DataBase Reference: 3,5-DIHYDROXYBENZOIC ACID 2,2,2-TRICHLOROETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIHYDROXYBENZOIC ACID 2,2,2-TRICHLOROETHYL ESTER(143330-91-0)
• EPA Substance Registry System: 3,5-DIHYDROXYBENZOIC ACID 2,2,2-TRICHLOROETHYL ESTER(143330-91-0)

Safety Data

• RIDADR: 1593
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 143330-91-0(Hazardous Substances Data)

Usage

Uses

Used in Personal Care Products:
Triclosan is used as an antimicrobial agent in personal care products such as soaps, lotions, and toothpastes. Its effectiveness in inhibiting bacterial and fungal growth helps maintain hygiene and prevent infections.
Used in Medical Devices:
Triclosan is also utilized in medical devices to prevent microbial contamination and ensure the safety and efficacy of these devices.
However, there are growing concerns about the potential health and environmental risks associated with triclosan, including hormone disruption, antibiotic resistance, and toxicity to aquatic organisms. As a result, regulatory agencies in some countries have taken steps to limit or ban its use in certain products.

InChI:InChI=1/C9H7Cl3O4/c10-9(11,12)4-16-8(15)5-1-6(13)3-7(14)2-5/h1-3,13-14H,4H2

Upstream product

• 115-20-8 1,1,1-trichloroethanol 
• 99-10-5 3,5-Dihydroxybenzoic acid 

Downstream Products

• 1033587-91-5 2,2,2-trichloroethyl 3,5-bis(perfluorobenzyloxy)benzoate 
• 143330-94-3 C₅₈H₃₅Cl₃O₁₇ 
• 143345-03-3 C₅₁H₃₁Cl₃O₁₄ 
• 143345-04-4 HO₂CC₆H₃(OC(O)C₆H₃(OC(O)C₆H₅)2)2 
• 143330-93-2 3,5-bis(benzoyloxy)benzoic acid 
• 474264-53-4 2',2',2'-trichloroethyl 3,5-bis[3',5'-bis(3'',5''-dimethoxybenzoyloxy)benzoyloxy]benzoate 
• 474264-54-5 3,5-bis[3',5'-bis(3'',5''-dimethoxybenzoyloxy)benzoyloxy]benzoic acid 
• 474264-52-3 3,5-bis(3',5'-dimethoxybenzoyloxy)benzoic acid 
• 562071-03-8 3,5-bis(4-hydroxy-2,3,5,6-tetrafluorobenzoyloxy)benzoic acid 
• 628685-37-0 3,5-Bis-[3,5-bis-(4-methoxycarbonyl-benzyloxy)-benzyloxy]-benzoic acid 
• 144840-94-8 C₄₉H₃₈O₁₀ 
• 628685-36-9 3,5-Bis-[3,5-bis-(4-methoxycarbonyl-benzyloxy)-benzyloxy]-benzoic acid 2,2,2-trichloro-ethyl ester 
• 562071-01-6 2,2,2-trichloroethyl 3,5-bis(4-benzyloxy-2,3,5,6-tetrafluorobenzoyloxy)benzoate 
• 474264-51-2 2',2',2'-trichloroethyl 3,5-bis(3',5'-dimethoxybenzoyloxy)benzoate 

Relevant articles and documents

Synthesis and characterization of a novel dimeric liquid crystalline dendrimer

A liquid crystalline aryl ester dendrimer containing 1,4-bis(4- hydroxybenzoyloxy) butane as the core moiety was successfully synthesized through an efficient convergent synthetic approach. The polyester fragment was synthesized through a process involving the condensation of 4-(dodecyloxy) benzoic acid with 2,2,2-trichloroethyl-3,5-dihydroxybenzoate. The coupling step was followed by removal of the 2,2,2-trichloroethyl ester group with zinc acetic acid. Characterization of all the synthesized compounds was carried out using spectroscopy methods. The thermal behavior of the acid dendritic wedges and the aryl ester dendrimer was investigated by differential scanning calorimetery and polarizing optical microscopy. Optical microscopy showed a focal-conic texture characteristic of the smectic A phase for novel dimeric dendrimer.

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Monodispersed Dendritic Polyesters with Removable Chain Ends: a Versatile Approach to Globular Macromolecules with Chemically Reversible Polarities

A versatile approach to dendritic macromolecules with aromatic polyester inner structure and a readily modified hydrophobic/hydrophilic "surface" is described.The polyester fragments are prepared by a convergent growth process involving 3,5-bis(benzyloxy)benzoic acid as the "surface" or chain-ending moiety and trichloroethyl 3,5-dihydroxybenzoate as the monomer unit.The key esterification step is accomplished in high yield using dicyclohexylcarbodiimide and 4-dimethylaminopyridinium toluene-p-sulfonate as condensing agents.The coupling step is followed by activation of the new focal point by removal of the trichloroethyl ester group with zinc-acetic acid.Repetition of this two-step process leads to large dendritic fragments that may be coupled to a polyfunctional core to complete the dendritic macromolecule.The chemistry chosen for this synthesis allows for subsequent selective removal of the numerous benzyl ether chain ends by hydrogenolysis to afford a dendritic macromolecule with phenolic chain ends.Further modification of the chain ends is readily accomplished in processes that effectively transform the initially hydrophobic dendritic molecule into one that is both hydrophilic and water-soluble.These transformations of the "surface" functionalities are also accompanied by drastic changes in glass transition behaviour.