143390-74-3Relevant articles and documents
Use of thiazoloisoindolinone derivatives as antiviral medicaments
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, (2008/06/13)
The present invention concerns the use of compounds of the general formula I STR1 for the preparation of medicaments for the treatment of viral or retroviral infections, whereby R signifies a hydrogen atom or a straight-chained or branched, saturated or u
Selective Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. New 2,3-Dihydrothiazoloisoindol-5(9bH)-ones and Related Compounds with Anti-HIV-1 Activity
Mertens, Alfred,Zilch, Harald,Koenig, Bernhard,Schaefer, Wolfgang,Poll, Thomas,et al.
, p. 2526 - 2535 (2007/10/02)
A series of substituted 2,3-dihydrothiazoloisoindol-5(9bH)-ones and related compounds 1-73 were synthesized and evaluated for their ability to inhibit reverse transcriptase (RT) of the human immune deficiency virus 1 (HIV-1) and replication of HIV-