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143520-19-8

2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE, with the CAS number 143520-19-8, is a complex carbohydrate derivative that plays a significant role in the field of organic chemistry, particularly in the synthesis of oligosaccharides. This molecule is characterized by its unique structure, which includes a tetra-O-benzyl-protected alpha-D-glucopyranosyl unit and a N,N,N',N'-tetramethylphosphorodiamidate group. The phosphorous moiety in this molecule serves as a leaving group, which is crucial for its reactivity and applications in chemical synthesis.

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  • [dimethylamino([3,4,5-tris(benzyloxy)-6-[(benzyloxy)methyl]oxan-2-yl]oxy)phosphoryl]dimethylamine

    Cas No: 143520-19-8

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  • 2,3,4,6-Tetra-O-benzyl-a-D-glucopyranosyl N,N,N,N-Tetramethylphosphorodiamidate (ca. 20% in Benzene)

    Cas No: 143520-19-8

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  • 143520-19-8 Structure

  • Basic information

    1. Product Name: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE
    2. Synonyms: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE;Ca.20%inbenzene;2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranosyl N,N,N',N'-Tetramethylphosphorodiamidate (ca. 20% in Benzene);2,3,4,6-Tetra-O-benzyl-alpha-D-glucopyranosyl N,N,N',N'-Tetramethylphosphorodiamidate (ca. 20% in Be;2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl N,N,N',N'-TetraMethylphosphorodiaMidate (ca. 20% in Benzene)
    3. CAS NO:143520-19-8
    4. Molecular Formula: C38H47N2O7P
    5. Molecular Weight: 674.76
    6. EINECS: N/A
    7. Product Categories: Biochemistry;Glucose;Glycosyl Donors;O-Substituted Sugars;Sugars
    8. Mol File: 143520-19-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerator
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE(143520-19-8)
    11. EPA Substance Registry System: 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE(143520-19-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. RIDADR: 1114
    5. WGK Germany:
    6. RTECS:
    7. HazardClass: 3
    8. PackingGroup: II
    9. Hazardous Substances Data: 143520-19-8(Hazardous Substances Data)

143520-19-8 Usage

Uses

Used in Organic Chemistry:
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE is used as a key intermediate in the synthesis of oligosaccharides. Its role as a glycosyl acceptor, along with the reactivity of its phosphorous leaving group, makes it a valuable compound for the construction of complex carbohydrate structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE is utilized for the development of novel drug candidates targeting various diseases, including cancer and infectious diseases. The ability to synthesize complex oligosaccharides using this compound can lead to the discovery of new therapeutic agents with improved efficacy and selectivity.
Used in Glycobiology Research:
2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE is also employed in glycobiology research, where it is used to study the structure, function, and biological roles of carbohydrates. 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE can be used to investigate the interactions between carbohydrates and proteins, as well as their involvement in cellular processes and signaling pathways.
Used in Material Science:
In the field of material science, 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE can be used to develop new materials with unique properties, such as self-assembling systems or stimuli-responsive materials. The ability to synthesize complex carbohydrate structures using this compound can lead to the creation of novel materials with potential applications in various industries, including biotechnology, pharmaceuticals, and nanotechnology.

Check Digit Verification of cas no

The CAS Registry Mumber 143520-19-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,5,2 and 0 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 143520-19:
(8*1)+(7*4)+(6*3)+(5*5)+(4*2)+(3*0)+(2*1)+(1*9)=98
98 % 10 = 8
So 143520-19-8 is a valid CAS Registry Number.

143520-19-8 Well-known Company Product Price

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  • TCI America

  • (T2197)  2,3,4,6-Tetra-O-benzyl-α-D-glucopyranosyl N,N,N',N'-Tetramethylphosphorodiamidate (ca. 20% in Benzene)  

  • 143520-19-8

  • 5g

  • 2,990.00CNY

  • Detail

143520-19-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[dimethylamino-[(2R,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]oxyphosphoryl]-N-methylmethanamine

1.2 Other means of identification

Product number -
Other names 2,3,4,6-TETRA-O-BENZYL-ALPHA-D-GLUCOPYRANOSYL N,N,N',N'-TETRAMETHYLPHOSPHORODIAMIDATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:143520-19-8 SDS

143520-19-8Relevant articles and documents

Oligosaccharide synthesis based on glycosyl donors and accepters carrying phosphorus-containing leaving groups

Hashimoto, Shun-Ichi,Sakamoto, Hiroki,Honda, Takeshi,Ikegami, Shiro

, p. 5181 - 5184 (2007/10/03)

Efficient synthetic strategy for oligosaccharides has been developed by exploiting the difference in anomeric reactivity between glycosyl donors and acceptors carrying phosphorus-containing leaving groups, wherein, the tetramethylphosphoroamidate group plays a pivotal role as anomeric protective group as well as leaving group.

An efficient construction of 1,2-trans-β-glycosidic linkages capitalizing on glycopyranosyl N,N,N',N'-tetramethylphosphoroamidates as shelf-stable glycosyl donors

Hashimoto,Yanagiya,Honda,Harada,Ikegami

, p. 3523 - 3526 (2007/10/02)

A highly stereocontrolled 1,2-trans-β-glycosidation reaction with or without neighbouring group participation has been developed by using benzyl- or benzoyl-protected glycopyranosyl N,N,N',N'-tetramethylphosphoramidates as shelf-stable glycosyl donors in

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