14357-76-7Relevant articles and documents
IMPROVED METHOD OF MANUFACTURING BUPRENORPHINE AND ANALOGUES THEREOF FROM ORIPAVINE
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Page/Page column 27, (2016/06/15)
The invention relates to an improved method of preparing buprenorphine, a salt thereof, analogues of buprenorphine and their salts. In particular, the invention relates to a method of preparing buprenorphine and related products and salts in economic and ecologic ways having increased yields.
A facile synthesis and structural verification of etorphine and dihydroetorphine from codeine
Huang, Xin-Ren,Srimurugan, Sankareswaran,Lee, Gene-Hsiang,Chena, Chinpiao
experimental part, p. 101 - 107 (2011/11/28)
In this study, an improved process for the synthesis of etorphine and dihydroetorphine from codeine with an overall yield of 2.7% and 1.5% respectively is described. The structure of 19-propylthevinol 7 was verfied by X-ray structure analysis. This result is promising for synthesizing various morphine-based drugs.